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Protein Overview: OAT

General Information:
Name(s) found: OAT [HGNC (HUGO)]
Description(s) found:
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  • pir||XNHUO ornithine-oxo-acid transaminase (EC 2.6.1.13) precursor [validated] - human [NCBI NR]
  • gi|55959997|emb|CAI17293.1| ornithine aminotransferase (gyrate atrophy) [Homo sapiens] [NCBI NR]
  • gi|48146207|emb|CAG33326.1| OAT [Homo sapiens] [NCBI NR]
  • gi|4557809|ref|NP_000265.1| ornithine aminotransferase precursor [Homo sapiens] [NCBI NR]
  • gi|4139656|pdb|2OAT|C Chain C, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI NR]
  • gi|4139655|pdb|2OAT|B Chain B, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI NR]
  • gi|4139654|pdb|2OAT|A Chain A, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI NR]
  • gi|386987|gb|AAA59957.1| ornithine aminotransferase [Homo sapiens] [NCBI NR]
  • gi|34138|emb|CAA68809.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|3114490|pdb|1OAT|C Chain C, Ornithine Aminotransferase [NCBI NR]
  • gi|3114489|pdb|1OAT|B Chain B, Ornithine Aminotransferase [NCBI NR]
  • gi|3114488|pdb|1OAT|A Chain A, Ornithine Aminotransferase [NCBI NR]
  • gi|189351|gb|AAA59959.1| ornithine aminotransferase [Homo sapiens] [NCBI NR]
  • gi|189348|gb|AAA36386.1| ornithine-delta-aminotransferase [NCBI NR]
  • gi|189329|gb|AAA59956.1| ornithine aminotransferase [Homo sapiens] [NCBI NR]
  • gi|189069120|dbj|BAG35458.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|16877350|gb|AAH16928.1| Ornithine aminotransferase (gyrate atrophy) [Homo sapiens] [NCBI NR]
  • gi|129018|sp|P04181.1|OAT_HUMAN RecName: Full=Ornithine aminotransferase, mitochondrial; AltName: Full=Ornithine--oxo-acid aminotransferase; Contains: RecName: Full=Ornithine aminotransferase, hepatic form; Contains: RecName: Full=Ornithine aminotransfera [NCBI NR]
  • gi|12654287|gb|AAH00964.1| Ornithine aminotransferase (gyrate atrophy) [Homo sapiens] [NCBI NR]
  • gi|119569657|gb|EAW49272.1| ornithine aminotransferase (gyrate atrophy), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119569656|gb|EAW49271.1| ornithine aminotransferase (gyrate atrophy), isoform CRA_a [Homo sapiens] [NCBI NR]
  • ornithine aminotransferase [HGNC (HUGO)]
  • Ornithine aminotransferase, mitochondrial OS=Homo sapiens GN=OAT PE=1 SV=1 [Swiss-Prot]
  • Ornithine aminotransferase, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • ornithine aminotransferase precursor; Ornithine aminotransferase [HMR_022704.fasta]
  • ornithine aminotransferase precursor [Homo sapiens]gi|12654287|gb|AAH00964.1| Ornithine aminotransferase, precursor [Homo sapiens]gi|16877350|gb|AAH16928.1| Ornithine aminotransferase, precursor [Homo sapiens]gi|34138|emb|CAA68809.1| unnamed protein pr [nrdb_11152004_Chlamydomonas]
  • Ornithine aminotransferase, mitochondrial precursor (Ornithine--oxo-acid aminotransferase) [Contains: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form] [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Ornithine aminotransferase, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_000274) ornithine aminotransferase precursor; Ornithine aminotransferase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • ornithine aminotransferase precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • ornithine aminotransferase precursor; Ornithine aminotransferase [Homo sapiens] [HumanGallus06162005.fasta]
  • Chain C, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain B, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Ornithine Aminotransferase Complexed With 5- Fluoromethylornithine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain C, Ornithine Aminotransferase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain B, Ornithine Aminotransferase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Ornithine Aminotransferase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ornithine aminotransferase (gyrate atrophy) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ornithine aminotransferase (gyrate atrophy), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Ornithine aminotransferase (gyrate atrophy) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • OAT [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ornithine-delta-aminotransferase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial [human-ipi-250309-contam.fasta]
  • Chain C, Ornithine Aminotransferase Complexed With 5-Fluoromethylornithine [nr-271106-contam.fasta]
  • Chain A, Ornithine Aminotransferase Complexed With 5-Fluoromethylornithine [nr-271106-contam.fasta]
  • Chain B, Ornithine Aminotransferase Complexed With 5-Fluoromethylornithine [nr-271106-contam.fasta]
  • ornithine aminotransferase isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_02-15-2010_reversed.fasta]
  • IPI:IPI00022334.1|SWISS-PROT:P04181|TREMBL:Q59HE2;Q68CS0|ENSEMBL:ENSP00000357838|REFSEQ:NP_000265|H-INV:HIT000037753|VEGA:OTTHUMP00000020690 Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial precursor ENSG00000065154 IPI00022334 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • ornithine aminotransferase, mitochondrial isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P04181;Q16068;Q16069;Q6IAV9;Q9UD03; RecName: Full=Ornithine aminotransferase, mitochondrial; AltName: Full=Ornithine--oxo-acid aminotransferase; Contains: RecName: Full=Ornithine aminotransferase, hepatic form; Contains: RecName: Full=Ornithine aminotransferase, renal form; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Ornithine aminotransferase, mitochondrial OS=Homo sapiens GN=OAT [011711_HMR.fasta]
  • IPI:IPI00022334.1|SWISS-PROT:P04181|TREMBL:D3DRF0|ENSEMBL:ENSP00000357838|REFSEQ:NP_000265|H-INV:HIT000037753|VEGA:OTTHUMP00000020690 Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=OAT Synonyms=DKFZp781A11155|GACR|HOGA|OATASE|OKT ornithine aminotransferase, mitochondrial isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00022334.1|SWISS-PROT:P04181|ENSEMBL:ENSP00000357838|REFSEQ:NP_000265|H-INV:HIT000037753|VEGA:OTTHUMP00000020690 Tax_Id=9606 Gene_Symbol=OAT Ornithine aminotransferase, mitochondrial [ipi.HUMAN.20110912.fasta]
  • Ornithine aminotransferase, mitochondrial GN=OAT [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSKLAHLQR FAVLSRGVHS SVASATSVAT KKTVQGPPTS DDIFEREYKY GAHNYHPLPV  60
   61 ALERGKGIYL WDVEGRKYFD FLSSYSAVNQ GHCHPKIVNA LKSQVDKLTL TSRAFYNNVL 120
  121 GEYEEYITKL FNYHKVLPMN TGVEAGETAC KLARKWGYTV KGIQKYKAKI VFAAGNFWGR 180
  181 TLSAISSSTD PTSYDGFGPF MPGFDIIPYN DLPALERALQ DPNVAAFMVE PIQGEAGVVV 240
  241 PDPGYLMGVR ELCTRHQVLF IADEIQTGLA RTGRWLAVDY ENVRPDIVLL GKALSGGLYP 300
  301 VSAVLCDDDI MLTIKPGEHG STYGGNPLGC RVAIAALEVL EEENLAENAD KLGIILRNEL 360
  361 MKLPSDVVTA VRGKGLLNAI VIKETKDWDA WKVCLRLRDN GLLAKPTHGD IIRFAPPLVI 420
  421 KEDELRESIE IINKTILSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..439] PSI-BLAST 113.0 Ornithine aminotransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-aminobutyrate transaminase activity
    		•  3.63797881096751 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  3.359406422625 bayes_pls_golite062009
  • transferase activity
    		•  2.59075614411581 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • adenosylmethionine-8-amino-7-oxononanoate transaminase activity
    		•  1.74778109525713 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.63055151623667 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.63055151623667 bayes_pls_golite062009
  • N-succinyltransferase activity
    		•  1.52003194822848 bayes_pls_golite062009
  • N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
    		•  1.4383564662931 bayes_pls_golite062009
  • glutamate decarboxylase activity
    		•  1.34215658716536 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.19150094103499 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.977210827616757 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.892872530648552 bayes_pls_golite062009
  • ligase activity
    		•  0.827063849687833 bayes_pls_golite062009
  • DNA binding
    		•  0.803965264969424 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase binding
    		•  0.78144409237642 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • transcription factor activity
    		•  0.597417107954964 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.54326874956263 bayes_pls_golite062009
  • binding
    		•  0.49769115245722 bayes_pls_golite062009
  • ornithine-oxo-acid transaminase activity
    		•  0.311107335626334 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.2609065149092 bayes_pls_golite062009
  • kynureninase activity
    		•  0.242752584041108 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.15938456446406 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.103986924428507 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.0254276656964899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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