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Protein Overview: EREG

General Information:
Name(s) found: EREG [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • epiregulin [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 169 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAGRRMEML CAGRVPALLL CLGFHLLQAV LSTTVIPSCI PGESSDNCTA LVQTEDNPRV  60
   61 AQVSITKCSS DMNGYCLHGQ CIYLVDMSQN YCRCEVGYTG VRCEHFFLTV HQPLSKEYVA 120
  121 LTVILIILFL ITVVGSTYYF CRWYRNRKSK EPKKEYERVT SGDPELPQV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] PSI-BLAST 10.69897 Solution structure and dynamics of the EGF/TGF-alpha chimera T1E

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ErbB-2 class receptor binding
    		•  5.8995982132645 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  5.34788747664513 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  4.96984057897789 bayes_pls_golite062009
  • growth factor activity
    		•  4.72461268561406 bayes_pls_golite062009
  • receptor binding
    		•  4.33045214660893 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  3.49243532917035 bayes_pls_golite062009
  • heparin binding
    		•  3.18889412817519 bayes_pls_golite062009
  • protein binding
    		•  3.02592228806142 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.79319890241656 bayes_pls_golite062009
  • binding
    		•  2.33940742543305 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.66401431847753 bayes_pls_golite062009
  • signal transducer activity
    		•  1.66401431847753 bayes_pls_golite062009
  • pattern binding
    		•  1.26957983931218 bayes_pls_golite062009
  • protein kinase activity
    		•  1.1805362342952 bayes_pls_golite062009
  • transcription factor binding
    		•  1.01285047489209 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.938291184527564 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.935213701014088 bayes_pls_golite062009
  • kinase activity
    		•  0.857148885514521 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.37481112933019 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.326255385249624 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle