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Protein Overview: PPAT

General Information:
Name(s) found: PPAT [HGNC (HUGO)]
Description(s) found:
Found 33 descriptions.
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  • phosphoribosyl pyrophosphate amidotransferase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 517 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELEELGIRE ECGVFGCIAS GEWPTQLDVP HVITLGLVGL QHRGQESAGI VTSDGSSVPT  60
   61 FKSHKGMGLV NHVFTEDNLK KLYVSNLGIG HTRYATTGKC ELENCQPFVV ETLHGKIAVA 120
  121 HNGELVNAAR LRKKLLRHGI GLSTSSDSEM ITQLLAYTPP QEQDDTPDWV ARIKNLMKEA 180
  181 PTAYSLLIMH RDVIYAVRDP YGNRPLCIGR LIPVSDINDK EKKTSETEGW VVSSESCSFL 240
  241 SIGARYYREV LPGEIVEISR HNVQTLDIIS RSEGNPVAFC IFEYVYFARP DSMFEDQMVY 300
  301 TVRYRCGQQL AIEAPVDADL VSTVPESATP AALAYAGKCG LPYVEVLCKN RYVGRTFIQP 360
  361 NMRLRQLGVA KKFGVLSDNF KGKRIVLVDD SIVRGNTISP IIKLLKESGA KEVHIRVASP 420
  421 PIKYPCFMGI NIPTKEELIA NKPEFDHLAE YLGANSVVYL SVEGLVSSVQ EGIKFKKQKE 480
  481 KKHDIMIQEN GNGLECFEKS GHCTACLTGK YPVELEW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..517] PSI-BLAST 88.0 Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uracil phosphoribosyltransferase activity
    		•  2.36237864658341 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.51875493459374 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • adenine phosphoribosyltransferase activity
    		•  0.985266832225609 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  0.625087274084001 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.283725923623827 bayes_pls_golite062009
  • ligase activity
    		•  0.204093345072151 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.0940838340168359 bayes_pls_golite062009
  • peptidase activity
    		•  0.0898497842822991 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.057753538747651 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.012663147802059 bayes_pls_golite062009
  • protein binding
    		•  0.00621436730716318 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle