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Protein Overview: LGALS7

General Information:
Name(s) found: LGALS7 [HGNC (HUGO)]
Description(s) found:
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  • gi|49522863|gb|AAH73743.1| Lectin, galactoside-binding, soluble, 7B [Homo sapiens] [NCBI NR]
  • gi|48145951|emb|CAG33198.1| LGALS7 [Homo sapiens] [NCBI NR]
  • gi|458703|gb|AAA86820.1| keratinocyte lectin 14 [NCBI NR]
  • gi|4504985|ref|NP_002298.1| galectin-7 [Homo sapiens] [NCBI NR]
  • gi|38494307|gb|AAH61588.1| Lectin, galactoside-binding, soluble, 7B [Homo sapiens] [NCBI NR]
  • pir||I55469 galectin-7 - human [NCBI NR]
  • gi|182132|gb|AAA67899.1| galectin-7 [NCBI NR]
  • gi|169214358|ref|XP_001721023.1| PREDICTED: similar to galectin-7 [Homo sapiens] [NCBI NR]
  • gi|1346431|sp|P47929.2|LEG7_HUMAN RecName: Full=Galectin-7; Short=Gal-7; AltName: Full=HKL-14; AltName: Full=PI7; AltName: Full=p53-induced gene 1 protein [NCBI NR]
  • gi|119577222|gb|EAW56818.1| hCG42850 [Homo sapiens] [NCBI NR]
  • gi|119577221|gb|EAW56817.1| hCG1776519 [Homo sapiens] [NCBI NR]
  • gi|113428637|ref|XP_001133982.1| PREDICTED: similar to Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced protein 1) [Homo sapiens] [NCBI NR]
  • gi|113428242|ref|XP_001128786.1| PREDICTED: similar to Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced protein 1) [Homo sapiens] [NCBI NR]
  • gi|109948279|ref|NP_001035972.1| galectin-7B [Homo sapiens] [NCBI NR]
  • lectin, galactoside-binding, soluble, 7 [HGNC (HUGO)]
  • Galectin-7 OS=Homo sapiens GN=LGALS7 PE=1 SV=2 [Swiss-Prot]
  • galectin 7 [hmr_yeast5_DM3-1_pombe.fasta]
  • galectin 7; lectin galactoside-binding soluble 7 [HMR_022704.fasta]
  • galectin 7 [Homo sapiens]gi|49522863|gb|AAH73743.1| Galectin 7 [Homo sapiens]gi|38494307|gb|AAH61588.1| Galectin 7 [Homo sapiens]gi|2135152|pir||I55469 galectin-7 - humangi|1346431|sp|P47929|LEG7_HUMAN Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced pr [nrdb_11152004_Chlamydomonas]
  • Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced protein 1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • (NM_002307) galectin 7; lectin galactoside-binding soluble 7 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • PREDICTED: similar to Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced protein 1) [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • galectin 7 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • hypothetical protein LOC653499 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Galectin 7 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • galectin 7; lectin galactoside-binding soluble 7 [Homo sapiens] [HumanGallus06162005.fasta]
  • Lectin, galactoside-binding, soluble, 7B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • galectin-7B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • galectin-7 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PREDICTED: similar to galectin-7 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG42850 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG1776519 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • LGALS7 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • keratinocyte lectin 14 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • galectin-7 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Lectin, galactoside-binding, soluble, 7 (galectin 7) [Homo sapiens] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=9606 GALECTIN 7 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Galectin-7; Short=Gal-7; AltName: Full=HKL-14; AltName: Full=PI7; AltName: Full=p53-induced gene 1 protein [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LGALS7;LGALS7B Galectin-7 [human-ipi-250309-contam.fasta]
  • IPI:IPI00219221.3|SWISS-PROT:P47929|TREMBL:Q6IB87|ENSEMBL:ENSP00000313571;ENSP00000367891|REFSEQ:NP_001035972;NP_002298|H-INV:HIT000264974|VEGA:OTTHUMP00000068268;OTTHUMP00000076991;OTTHUMP00000077184 Tax_Id=9606 Gene_Symbol=LGALS7B;LGALS7 Galectin-7 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Galectin-7 [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=LOC732032;LOC653499;LOC728910;LGALS7 Galectin-7 ENSG00000178934 IPI00219221 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LGALS7;LOC732032;LOC653499;LOC728910 Galectin-7 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • P47929;Q6IB87; RecName: Full=Galectin-7; AltName: Full=HKL-14; AltName: Full=PI7; AltName: Full=p53-induced gene 1 protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Galectin-7 OS=Homo sapiens GN=LGALS7 [011711_HMR.fasta]
  • IPI:IPI00219221.3|SWISS-PROT:P47929|ENSEMBL:ENSP00000313571;ENSP00000367891|REFSEQ:NP_001035972;NP_002298|H-INV:HIT000264974|VEGA:OTTHUMP00000068268;OTTHUMP00000076991;OTTHUMP00000077184 Tax_Id=9606 Gene_Symbol=LGALS7;LGALS7B Galectin-7 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=LGALS7 Synonyms=GAL7|LGALS7A galectin-7 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • GeneSymbol=LGALS7B Synonyms=GAL7|Gal-7|HKL-14|LGALS7|MGC75149|MGC88745|PI7 galectin-7 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00219221.3|SWISS-PROT:P47929|ENSEMBL:ENSP00000313571;ENSP00000367891|REFSEQ:NP_001035972;NP_002298|H-INV:HIT000264974 Tax_Id=9606 Gene_Symbol=LGALS7;LGALS7B Galectin-7 [ipi.HUMAN.20110912.fasta]
  • Galectin-7 GN=LGALS7 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=LGALS7B;LGALS7 Galectin-7 [human-ipi-270911-contam-BSA.fasta]
  • IPI:IPI00219221.3|SWISS-PROT:P47929|ENSEMBL:ENSP00000313571;ENSP00000367891|REFSEQ:NP_001035972;NP_002298|H-INV:HIT000264974 Tax_Id=9606 Gene_Symbol=LGALS7B;LGALS7 Galectin-7 [ipi.HUMAN.fasta.20110927]
    • Organism: Homo sapiens
    Length: 136 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH FNPRLDTSEV  60
   61 VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA VVGDAQYHHF RHRLPLARVR 120
  121 LVEVGGDVQL DSVRIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..136] PSI-BLAST 42.09691 S-lectin, different isoforms

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • sugar binding
    		•  3.34064405064299 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.70103238455595 bayes_pls_golite062009
  • binding
    		•  2.40096962515027 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.35851723238763 bayes_pls_golite062009
  • monosaccharide binding
    		•  2.09529521879228 bayes_pls_golite062009
  • carbohydrate binding
    		•  1.90829797790335 bayes_pls_golite062009
  • protein binding
    		•  1.80794638640093 bayes_pls_golite062009
  • heparin binding
    		•  1.60966215355794 bayes_pls_golite062009
  • extracellular matrix binding
    		•  1.41229380365824 bayes_pls_golite062009
  • fibronectin binding
    		•  1.10309233016451 bayes_pls_golite062009
  • galactoside binding
    		•  1.08479183125487 bayes_pls_golite062009
  • pattern binding
    		•  0.969915174528009 bayes_pls_golite062009
  • receptor binding
    		•  0.9012250808046 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.5068011550246 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.372701974560119 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.216086300988177 bayes_pls_golite062009
  • DNA binding
    		•  0.157628282318248 bayes_pls_golite062009
  • growth factor activity
    		•  0.119475011376319 bayes_pls_golite062009
  • fibroblast growth factor 2 binding
    		•  0.0714976455077903 bayes_pls_golite062009
  • fibrinogen binding
    		•  0.0714976455077903 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle