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Protein Overview: NOB1

General Information:
Name(s) found: NOB1 [HGNC (HUGO)]
Description(s) found:
Found 26 descriptions.
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  • NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP  60
   61 EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE 120
  121 TPLHISGFHL PYKPKPPQET EKGHSACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE 180
  181 DVPSEEEEEE ENGFEDRKDD SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV RVGCLTTDFA 240
  241 MQNVLLQMGL HVLAVNGMLI REARSYILRC HGCFKTTSDM SRVFCSHCGN KTLKKVSVTV 300
  301 SDDGTLHMHF SRNPKVLNPR GLRYSLPTPK GGKYAINPHL TEDQRFPQLR LSQKARQKTN 360
  361 VFAPDYIAGV SPFVENDISS RSATLQVRDS TLGAGRRRLN PNASRKKFVK KR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..170] FFAS03 1.41 Hypothetical protein AF0591
    2 View Details [171..236] deduced N/A No confident structure predictions are available.
    3 View Details [237..326] PSI-BLAST 30.30103 Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA
    4 View Details [327..412] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  2.49612885073648 bayes_pls_golite062009
  • exonuclease activity
    		•  2.20856194655683 bayes_pls_golite062009
  • DNA binding
    		•  1.98330542087379 bayes_pls_golite062009
  • binding
    		•  1.91435224223408 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.86243238793767 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  1.74349203224875 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.68760157046614 bayes_pls_golite062009
  • endonuclease activity
    		•  1.2840172881923 bayes_pls_golite062009
  • catalytic activity
    		•  1.27951740231695 bayes_pls_golite062009
  • flap endonuclease activity
    		•  1.17726395799783 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.07360773846975 bayes_pls_golite062009
  • 5'-3' exonuclease activity
    		•  0.974028111038185 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.867731336605067 bayes_pls_golite062009
  • hydrolase activity
    		•  0.827276601361763 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.79417076649627 bayes_pls_golite062009
  • protein binding
    		•  0.695466920831325 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.267787854683683 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.260397221344929 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.175191448555725 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • RNA binding
    		•  2.67504868533195 bayes_pls_golite062009
  • binding
    		•  2.1226043957694 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.26170105245043 bayes_pls_golite062009
  • protein binding
    		•  0.874974846355882 bayes_pls_golite062009
  • catalytic activity
    		•  0.316629025709297 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle