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Protein Overview: gi|4454704, gi|1...

General Information:
Name(s) found: gi|8895208 [NCBI NR]
gi|6841360 [NCBI NR]
gi|5803102 [NCBI NR]
gi|4808625 [NCBI NR]
gi|4454704 [NCBI NR]
gi|33337722 [NCBI NR]
gi|18605583 [NCBI NR]
gi|12804159 [NCBI NR]
gi|12643874 [NCBI NR]
gi|119619553 [NCBI NR]
gi|119619552 [NCBI NR]
gi|119619550 [NCBI NR]
Description(s) found:
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  • gi|8895208|gb|AAF80854.1|AF167173_1 MSL3-1 protein [Homo sapiens] [NCBI NR]
  • gi|6841360|gb|AAF29033.1|AF161546_1 HSPC061 [Homo sapiens] [NCBI NR]
  • gi|5803102|ref|NP_006782.1| MORF-related gene 15 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|4808625|gb|AAD29872.1|AF100615_1 MRG15 protein [Homo sapiens] [NCBI NR]
  • gi|4454704|gb|AAD20970.1| HSPC008 [Homo sapiens] [NCBI NR]
  • gi|33337722|gb|AAQ13497.1|AF109188_1 FWP006 [Homo sapiens] [NCBI NR]
  • gi|18605583|gb|AAH22845.1| Mortality factor 4 like 1 [Homo sapiens] [NCBI NR]
  • gi|12804159|gb|AAH02936.1| Mortality factor 4 like 1 [Homo sapiens] [NCBI NR]
  • sp|Q9UBU8|MG15_HUMAN Transcription factor-like protein MRG15 (MORF-related gene 15 protein) (Mortality factor 4-like 1) (MSL3-1 protein) (HSPC008/HSPC061) [NCBI NR]
  • gi|119619553|gb|EAW99147.1| mortality factor 4 like 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119619552|gb|EAW99146.1| mortality factor 4 like 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119619550|gb|EAW99144.1| mortality factor 4 like 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • (Q9UBU8) Transcription factor-like protein MRG15 (MORF-related gene 15 protein) (Mortality factor 4-like 1) (MSL3-1 protein) (HSPC008/HSPC061) [Swiss-Prot]
  • Transcription factor-like protein MRG15 [hmr_yeast5_DM3-1_pombe.fasta]
  • MORF-related gene 15 isoform 1; MORF-related gene 15 [HMR_022704.fasta]
  • MORF-related gene 15 isoform 1 [Homo sapiens]gi|13277348|ref|NP_077751.1| mortality factor 4 like 1 [Mus musculus]gi|52789305|gb|AAH83118.1| Mortality factor 4 like 1 [Mus musculus]gi|54035370|gb|AAH84008.1| Unknown (protein for MGC:98166) [Xenopus lae [nrdb_11152004_Chlamydomonas]
  • (NM_006791) MORF-related gene 15 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • MORF-related gene 15 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • MORF-related gene 15 isoform 1; MORF-related gene 15 [Homo sapiens] [HumanGallus06162005.fasta]
  • MORF-related gene 15 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • mortality factor 4 like 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Mortality factor 4 like 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • FWP006 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • HSPC008 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • HSPC061 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MSL3-1 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MRG15 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 TRANSCRIPTION FACTOR-LIKE PROTEIN MRG15 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • IPI:IPI00930346.1|SWISS-PROT:Q9UBU8-2|ENSEMBL:ENSP00000408880|REFSEQ:NP_006782|VEGA:OTTHUMP00000176031 Tax_Id=9606 Gene_Symbol=MORF4L1 Isoform 2 of Mortality factor 4-like protein 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=MORF4L1 Isoform 2 of Mortality factor 4-like protein 1 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • mortality factor 4-like protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 2 of Mortality factor 4-like protein 1 OS=Homo sapiens GN=MORF4L1 [011711_HMR.fasta]
  • IPI:IPI00930346.1|SWISS-PROT:Q9UBU8-2|TREMBL:D3DW88|ENSEMBL:ENSP00000408880|REFSEQ:NP_006782|VEGA:OTTHUMP00000176031 Tax_Id=9606 Gene_Symbol=MORF4L1 Isoform 2 of Mortality factor 4-like protein 1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=MORF4L1 Synonyms=Eaf3|HsT17725|MEAF3|MGC10631|MORFRG15|MRG15|S863-6 mortality factor 4-like protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00930346.1|SWISS-PROT:Q9UBU8-2|TREMBL:B7Z6R1;Q0VAE4|ENSEMBL:ENSP00000408880|REFSEQ:NP_006782 Tax_Id=9606 Gene_Symbol=MORF4L1 Isoform 2 of Mortality factor 4-like protein 1 [ipi.HUMAN.20110912.fasta]
  • Isoform 2 of Mortality factor 4-like protein 1 GN=MORF4L1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of Q9UBU8, Isoform 2 of Mortality factor 4-like protein 1 OS=Homo sapiens GN=MORF4L1 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKQDPKPK FQEGERVLCF HGPLLYEAKC VKVAIKDKQV KYFIHYSGWN KNWDEWVPES  60
   61 RVLKYVDTNL QKQRELQKAN QEQYAEGKMR GAAPGKKTSG LQQKNVEVKT KKNKQKTPGN 120
  121 GDGGSTSETP QPPRKKRARV DPTVENEETF MNRVEVKVKI PEELKPWLVD DWDLITRQKQ 180
  181 LFYLPAKKNV DSILEDYANY KKSRGNTDNK EYAVNEVVAG IKEYFNVMLG TQLLYKFERP 240
  241 QYAEILADHP DAPMSQVYGA PHLLRLFVRI GAMLAYTPLD EKSLALLLNY LHDFLKYLAK 300
  301 NSATLFSASD YEVAPPEYHR KAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 29.154902 No description for 2efiA was found.
    2 View Details [140..323] PSI-BLAST 69.0 Crystal Structure of the MRG15 MRG domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription repressor activity
    		•  4.08500855631983 bayes_pls_golite062009
  • chromatin binding
    		•  3.84065302930105 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64390820819794 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.42338304360938 bayes_pls_golite062009
  • binding
    		•  3.06758476214113 bayes_pls_golite062009
  • protein binding
    		•  2.66728689880621 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19167058827256 bayes_pls_golite062009
  • DNA binding
    		•  2.05514577638135 bayes_pls_golite062009
  • histone binding
    		•  2.00388175060339 bayes_pls_golite062009
  • satellite DNA binding
    		•  1.4681464542396 bayes_pls_golite062009
  • transcription activator activity
    		•  1.46529895769882 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.10020047862576 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.998957812785999 bayes_pls_golite062009
  • general transcriptional repressor activity
    		•  0.75184432495983 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.726970683178132 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.494788451379878 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.294457188332415 bayes_pls_golite062009
  • catalytic activity
    		•  0.14067200158938 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle