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View Structure Prediction Details

Protein: gi|4454704, gi|1...
Organism: Homo sapiens
Length: 323 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4454704, gi|1....

Description E-value Query
Range		 Subject
Range
gi|94406757 - gi|94406757|ref|XP_981969.1| PREDICTED: similar to mortality factor 4 like 1 isoform b [Mus musculus...
 0.0 [1..323] [1..323]
MO4L1_RAT - Mortality factor 4-like protein 1 OS=Rattus norvegicus GN=Morf4l1 PE=2 SV=1
 0.0 [1..323] [1..323]
gi|67968852 - gi|67968852|dbj|BAE00783.1| unnamed protein product [Macaca fascicularis]
 0.0 [1..323] [1..323]
MO4L1_PONAB - Mortality factor 4-like protein 1 OS=Pongo abelii GN=MORF4L1 PE=2 SV=1
MO4L1_PONPY - Mortality factor 4-like protein 1 - Pongo pygmaeus (Orangutan)
 0.0 [1..323] [1..323]
gi|45767884 - gi|45767884|gb|AAH67826.1| Mortality factor 4 like 1 [Homo sapiens]
 0.0 [1..323] [1..323]
gi|84105337 - gi|84105337|ref|NP_001032253.1| mortality factor 4 like 1 isoform 2 [Gallus gallus]
 0.0 [1..323] [1..323]

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Predicted Domain #1
Region A:
Residues: [1-139] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKQDPKPK FQEGERVLCF HGPLLYEAKC VKVAIKDKQV KYFIHYSGWN KNWDEWVPES  60
   61 RVLKYVDTNL QKQRELQKAN QEQYAEGKMR GAAPGKKTSG LQQKNVEVKT KKNKQKTPGN 120
  121 GDGGSTSETP QPPRKKRAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.154902
Match: 2efiA
Description: No description for 2efiA was found.

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
chromatin binding 3.84065302930105 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
satellite DNA binding 1.4681464542396 bayes_pls_golite062009
transcription activator activity 1.46529895769882 bayes_pls_golite062009
sequence-specific DNA binding 1.10020047862576 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [140-323] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDPTVENEET FMNRVEVKVK IPEELKPWLV DDWDLITRQK QLFYLPAKKN VDSILEDYAN  60
   61 YKKSRGNTDN KEYAVNEVVA GIKEYFNVML GTQLLYKFER PQYAEILADH PDAPMSQVYG 120
  121 APHLLRLFVR IGAMLAYTPL DEKSLALLLN YLHDFLKYLA KNSATLFSAS DYEVAPPEYH 180
  181 RKAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.0
Match: 2aqlA
Description: Crystal Structure of the MRG15 MRG domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle