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Protein Overview: PIGK

General Information:
Name(s) found: PIGK [HGNC (HUGO)]
Description(s) found:
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  • gi|56203062|emb|CAI21819.1| phosphatidylinositol glycan anchor biosynthesis, class K [Homo sapiens] [NCBI NR]
  • gi|2558891|gb|AAB81597.1| GPI transamidase [Homo sapiens] [NCBI NR]
  • gi|23199983|ref|NP_005473.1| phosphatidylinositol glycan anchor biosynthesis, class K precursor [Homo sapiens] [NCBI NR]
  • gi|22001630|sp|Q92643.2|GPI8_HUMAN RecName: Full=GPI-anchor transamidase; Short=GPI transamidase; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; Short=PIG-K; Short=hGPI8; Flags: Precursor [NCBI NR]
  • gi|189053598|dbj|BAG35850.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|18088439|gb|AAH20737.1| Phosphatidylinositol glycan anchor biosynthesis, class K [Homo sapiens] [NCBI NR]
  • gi|119626785|gb|EAX06380.1| phosphatidylinositol glycan, class K, isoform CRA_a [Homo sapiens] [NCBI NR]
  • phosphatidylinositol glycan anchor biosynthesis, class K [HGNC (HUGO)]
  • GPI-anchor transamidase OS=Homo sapiens GN=PIGK PE=1 SV=2 [Swiss-Prot]
  • GPI-anchor transamidase [hmr_yeast5_DM3-1_pombe.fasta]
  • phosphatidylinositol glycan, class K precursor [HMR_022704.fasta]
  • phosphatidylinositol glycan, class K precursor [Homo sapiens]gi|18088439|gb|AAH20737.1| Phosphatidylinositol glycan, class K, precursor [Homo sapiens]gi|2558891|gb|AAB81597.1| GPI transamidase [Homo sapiens]gi|22001630|sp|Q92643|GPI8_HUMAN GPI-anchor t [nrdb_11152004_Chlamydomonas]
  • GPI-anchor transamidase precursor (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis, class K protein) (PIG-K) (hGPI8) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 GPI-anchor transamidase precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • phosphatidylinositol glycan anchor biosynthesis, class K precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • phosphatidylinositol glycan, class K precursor [Homo sapiens] [HumanGallus06162005.fasta]
  • GPI-anchor transamidase precursor (GPI transamidase) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) (hGPI8) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidylinositol glycan anchor biosynthesis, class K [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidylinositol glycan, class K, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Phosphatidylinositol glycan anchor biosynthesis, class K [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • GPI transamidase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 GPI-ANCHOR TRANSAMIDASE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PIGK GPI-anchor transamidase [human-ipi-250309-contam.fasta]
  • phosphatidylinositol glycan, class K [Homo sapiens] [nr-271106-contam.fasta]
  • IPI:IPI00022543.4|SWISS-PROT:Q92643|TREMBL:B2R7K3|ENSEMBL:ENSP00000359848|REFSEQ:NP_005473|H-INV:HIT000062696|VEGA:OTTHUMP00000011255 Tax_Id=9606 Gene_Symbol=PIGK GPI-anchor transamidase [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PIGK GPI-anchor transamidase precursor ENSG00000142892 IPI00478201 IPI00022543 IPI00514325 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PIGK GPI-anchor transamidase precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • GPI-anchor transamidase precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q92643;B2R7K3;O14822;Q5TG77; RecName: Full=GPI-anchor transamidase; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; AltName: Full=GPI8 homolog; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • GPI-anchor transamidase OS=Homo sapiens GN=PIGK [011711_HMR.fasta]
  • IPI:IPI00022543.4|SWISS-PROT:Q92643|ENSEMBL:ENSP00000359848|REFSEQ:NP_005473|H-INV:HIT000062696|VEGA:OTTHUMP00000011255 Tax_Id=9606 Gene_Symbol=PIGK GPI-anchor transamidase [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=PIGK Synonyms=GPI8|MGC22559 GPI-anchor transamidase precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • GPI-anchor transamidase GN=PIGK [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 395 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTDSLSRA ATVLATVLLL SFGSVAASHI EDQAEQFFRS GHTNNWAVLV CTSRFWFNYR  60
   61 HVANTLSVYR SVKRLGIPDS HIVLMLADDM ACNPRNPKPA TVFSHKNMEL NVYGDDVEVD 120
  121 YRSYEVTVEN FLRVLTGRIP PSTPRSKRLL SDDRSNILIY MTGHGGNGFL KFQDSEEITN 180
  181 IELADAFEQM WQKRRYNELL FIIDTCQGAS MYERFYSPNI MALASSQVGE DSLSHQPDPA 240
  241 IGVHLMDRYT FYVLEFLEEI NPASQTNMND LFQVCPKSLC VSTPGHRTDL FQRDPKNVLI 300
  301 TDFFGSVRKV EITTETIKLQ QDSEIMESSY KEDQMDEKLM EPLKYAEQLP VAQIIHQKPK 360
  361 LKDWHPPGGF ILGLWALIIM VFFKTYGIKH MKFIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] FFAS03 1.64 Crystal Structure of Caspase-1 from Spodoptera frugiperda
    2 View Details [308..395] MSA 3.075992 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.91027458364943 bayes_pls_golite062009
  • binding
    		•  1.79991239685564 bayes_pls_golite062009
  • peptidase activity
    		•  1.03949773191901 bayes_pls_golite062009
  • catalytic activity
    		•  0.976874866811795 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.690246965666701 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.5642733654889 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.373000256936384 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle