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Protein Overview: gi|1743871, gi|5...

General Information:
Name(s) found: gi|55960957 [NCBI NR]
gi|4505815 [NCBI NR]
gi|1743871 [NCBI NR]
gi|158255466 [NCBI NR]
gi|119573846 [NCBI NR]
Description(s) found:
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  • gi|55960957|emb|CAI16387.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Homo sapiens] [NCBI NR]
  • gi|4505815|ref|NP_003548.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha isoform 2 [Homo sapiens] [NCBI NR]
  • gi|1743871|gb|AAC50910.1| 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [Homo sapiens] [NCBI NR]
  • gi|158255466|dbj|BAF83704.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119573846|gb|EAW53461.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, isoform CRA_c [Homo sapiens] [NCBI NR]
  • 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [hmr_yeast5_DM3-1_pombe.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [HMR_022704.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Homo sapiens]gi|1743871|gb|AAC50910.1| 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Splice Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_003557) phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type I alpha [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, isoform CRA_c [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 68 KDA TYPE I PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE ALPHA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha isoform 2 [Homo sapiens] [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PIP5K1A Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha [human-ipi-250309-contam.fasta]
  • IPI:IPI00163602.1|SWISS-PROT:Q99755-3|TREMBL:A8K4Q0;P78517|ENSEMBL:ENSP00000271663|REFSEQ:NP_003548|VEGA:OTTHUMP00000014290 Tax_Id=9606 Gene_Symbol=PIP5K1A Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • phosphatidylinositol-4-phosphate 5-kinase type-1 alpha isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha OS=Homo sapiens GN=PIP5K1A [011711_HMR.fasta]
  • IPI:IPI00163602.1|SWISS-PROT:Q99755-3|TREMBL:P78517|ENSEMBL:ENSP00000271663|REFSEQ:NP_003548|VEGA:OTTHUMP00000014290 Tax_Id=9606 Gene_Symbol=PIP5K1A Isoform 3 of Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=PIP5K1A Synonyms=- phosphatidylinositol-4-phosphate 5-kinase type-1 alpha isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Isoform 3 of Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Homo sapiens GN=PIP5K1A [uniprot-human-120502.fasta]
  • Isoform 3 of Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha GN=PIP5K1A [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of Q99755, Isoform 3 of Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Homo sapiens GN=PIP5K1A [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 549 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASASSGPSS SVGFSSFDPA VPSCTLSSAS GIKRPMASEV PYASGMPIKK IGHRSVDSSG  60
   61 ETTYKKTTSS ALKGAIQLGI THTVGSLSTK PERDVLMQDF YVVESIFFPS EGSNLTPAHH 120
  121 YNDFRFKTYA PVAFRYFREL FGIRPDDYLY SLCSEPLIEL CSSGASGSLF YVSSDDEFII 180
  181 KTVQHKEAEF LQKLLPGYYM NLNQNPRTLL PKFYGLYCVQ AGGKNIRIVV MNNLLPRSVK 240
  241 MHIKYDLKGS TYKRRASQKE REKPLPTFKD LDFLQDIPDG LFLDADMYNA LCKTLQRDCL 300
  301 VLQSFKIMDY SLLMSIHNID HAQREPLSSE TQYSVDTRRP APQKALYSTA MESIQGEARR 360
  361 GGTMETDDHM GGIPARNSKG ERLLLYIGII DILQSYRFVK KLEHSWKALV HDGDTVSVHR 420
  421 PGFYAERFQR FMCNTVFKKI PLKPSPSKKF RSGSSFSRRA GSSGNSCITY QPSVSGEHKA 480
  481 QVTTKAEVEP GVHLGRPDVL PQTPPLEEIS EGSPIPDPSF SPLVGETLQM LTTSTTLEKL 540
  541 EVAESEFTH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..436] PSI-BLAST 114.0 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
    2 View Details [437..549] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • inositol or phosphatidylinositol kinase activity
    		•  4.31726963575315 bayes_pls_golite062009
  • lipid kinase activity
    		•  3.63026201392483 bayes_pls_golite062009
  • phosphatidylinositol phosphate kinase activity
    		•  3.29315211323714 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.8512866333787 bayes_pls_golite062009
  • kinase activity
    		•  2.68971389233526 bayes_pls_golite062009
  • 1-phosphatidylinositol-4-phosphate 5-kinase activity
    		•  2.65186975336776 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.31077377326314 bayes_pls_golite062009
  • catalytic activity
    		•  1.87792712964225 bayes_pls_golite062009
  • binding
    		•  1.23659721062619 bayes_pls_golite062009
  • transferase activity
    		•  1.20817067352467 bayes_pls_golite062009
  • ligase activity
    		•  0.435608917599349 bayes_pls_golite062009
  • protein kinase activity
    		•  0.422676745032915 bayes_pls_golite062009
  • protein binding
    		•  0.382966234080422 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.189737258618863 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.14608192065514 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle