YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|1743871, gi|5...
Organism: Homo sapiens
Length: 549 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1743871, gi|5....

Description E-value Query
Range
Subject
Range
gi|212276254, gi... - gi|212276254|ref|NP_001131030.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Pan trogl...
0.0 [18..549] [18..550]
gi|212276113, gi... - gi|212276113|ref|NP_001130039.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Macaca mu...
0.0 [18..549] [18..550]
PIP5K1A - phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
0.0 [18..549] [18..562]
gi|110835721 - gi|110835721|ref|NP_001036086.1| phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [Rattus no...
0.0 [14..549] [13..546]

Back

Predicted Domain #1
Region A:
Residues: [1-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASASSGPSS SVGFSSFDPA VPSCTLSSAS GIKRPMASEV PYASGMPIKK IGHRSVDSSG  60
   61 ETTYKKTTSS ALKGAIQLGI THTVGSLSTK PERDVLMQDF YVVESIFFPS EGSNLTPAHH 120
  121 YNDFRFKTYA PVAFRYFREL FGIRPDDYLY SLCSEPLIEL CSSGASGSLF YVSSDDEFII 180
  181 KTVQHKEAEF LQKLLPGYYM NLNQNPRTLL PKFYGLYCVQ AGGKNIRIVV MNNLLPRSVK 240
  241 MHIKYDLKGS TYKRRASQKE REKPLPTFKD LDFLQDIPDG LFLDADMYNA LCKTLQRDCL 300
  301 VLQSFKIMDY SLLMSIHNID HAQREPLSSE TQYSVDTRRP APQKALYSTA MESIQGEARR 360
  361 GGTMETDDHM GGIPARNSKG ERLLLYIGII DILQSYRFVK KLEHSWKALV HDGDTVSVHR 420
  421 PGFYAERFQR FMCNTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1bo1A
Description: Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inositol or phosphatidylinositol kinase activity 4.31726963575315 bayes_pls_golite062009
lipid kinase activity 3.63026201392483 bayes_pls_golite062009
phosphatidylinositol phosphate kinase activity 3.29315211323714 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.8512866333787 bayes_pls_golite062009
kinase activity 2.68971389233526 bayes_pls_golite062009
1-phosphatidylinositol-4-phosphate 5-kinase activity 2.65186975336776 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.31077377326314 bayes_pls_golite062009
catalytic activity 1.87792712964225 bayes_pls_golite062009
binding 1.23659721062619 bayes_pls_golite062009
transferase activity 1.20817067352467 bayes_pls_golite062009
ligase activity 0.435608917599349 bayes_pls_golite062009
protein kinase activity 0.422676745032915 bayes_pls_golite062009
protein binding 0.382966234080422 bayes_pls_golite062009
protein serine/threonine kinase activity 0.189737258618863 bayes_pls_golite062009
acid-amino acid ligase activity 0.14608192065514 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [437-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKKIPLKPSP SKKFRSGSSF SRRAGSSGNS CITYQPSVSG EHKAQVTTKA EVEPGVHLGR  60
   61 PDVLPQTPPL EEISEGSPIP DPSFSPLVGE TLQMLTTSTT LEKLEVAESE FTH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle