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Protein Overview: gi|25535937, gi|...

General Information:
Name(s) found: gi|7242963 [NCBI NR]
gi|25535937 [NCBI NR]
Description(s) found:
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  • gi|7242963|dbj|BAA92542.1| KIAA1304 protein [Homo sapiens] [NCBI NR]
  • pir||G59436 KIAA1304 protein [imported] - human [NCBI NR]
  • Hypothetical protein KIAA1304 [hmr_yeast5_DM3-1_pombe.fasta]
  • KIAA1304 protein [imported] - humangi|7242963|dbj|BAA92542.1| KIAA1304 protein [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • KIAA1304 protein [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta]
    • Organism: Homo sapiens
    Length: 1051 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNHPLASLLS LEIRAQLVEQ QKCLEQQTEM RVQLLQDLQD FFRKKAEIET EYSRNLEKLA  60
   61 ERFMAKTRST KDHQQYKKDQ NLLSPVNCWY LLLNQVRRES KDHATLSDIY LNNVIMRFMQ 120
  121 ISEDSTRMFK KSKEIAFQLH EDLMKVLNEL YTVMKTYHMY HAESISAESK LKEAEKQEEK 180
  181 QIGRSGDPVF HIRLEERHQR RSSVKKIEKM KEKRQAKYSE NKLKSIKARN EYLLTLEATN 240
  241 ASVFKYYIHD LSDLIDCCDL GYHASLNRAL RTYLSAEYNL ETSRHEGLDI IENAVDNLEP 300
  301 RSDKQRFMEM YPAAFCPPMK FEFQSHMGDE VCQVSAQQPV QAELMLRYQQ LQSRLATLKI 360
  361 ENEEVKKTTE ATLQTIQDMV TIEDYDVSEC FQHSRSTESV KSTVSETYLS KPSIAKRRAN 420
  421 QQETEQFYFM KLREYLEGSN LITKLQAKHD LLQRTLGEGH RAEYMTTSRG RRNSHTRHQD 480
  481 SGQVIPLIVE SCIRFINLYG LQHQGIFRVS GSQVEVNDIK NSFERGENPL ADDQSNHDIN 540
  541 SVAGVLKLYF RGLENPLFPK ERFNDLISCI RIDNLYERAL HIRKLLLTLP RSVLIVMRYL 600
  601 FAFLNHLSQY SDENMMDPYN LAICFGPTLM PVPEIQDQVS CQAHVNEIIK TIIIHHETIF 660
  661 PDAKELDGPV YEKCMAGDDY CDSPYSEHGT LEEVDQDAGT EPHTSEDECE PIEAIAKFDY 720
  721 VGRSARELSF KKGASLLLYH RASEDWWEGR HNGIDGLVPH QYIVVQDMDD TFSDTLSQKA 780
  781 DSEASSGPVT EDKSSSKDMN SPTDRHPDGY LARQRKRGEP PPPVRRPGRT SDGHCPLHPP 840
  841 HALSNSSVDL GSPSLASHPR GLLQNRGLNN DSPERRRRPG HGSLTNISRH DSLKKIDSPP 900
  901 IRRSTSSGQY TGFNDHKPLD PETIAQDIEE TMNTALNELR ELERQSTAKH APDVVLDTLE 960
  961 QVKNSPTPAT STESLSPLHN VALRSSEPQI RRSTSSSSDT MSTFKPMVAP RMGVQLKPPA1020
 1021 LRPKPAVLPK TNPTIGPAPP PQGPTDKSCT M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 19.0 Heavy meromyosin subfragment
    2 View Details [380..663] PSI-BLAST 34.0 Crystal Structure of the Human Beta2-Chimaerin
    3 View Details [664..905] FFAS03 3.82 p47pox (neutrophil cytosolic factor 1)
    4 View Details [906..1051] MSA 7.277996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  4.48279904625182 bayes_pls_golite062009
  • binding
    		•  2.79128751898373 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.70614727793157 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.68579854252375 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.06038764955701 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.9750017471254 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.95738547986197 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.39616729198212 bayes_pls_golite062009
  • Rho GTPase binding
    		•  1.34980300847466 bayes_pls_golite062009
  • protein binding
    		•  1.29100556128076 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.25507073225414 bayes_pls_golite062009
  • signal transducer activity
    		•  1.25507073225414 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.09070479183477 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.08577758274384 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.967362611034944 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.958295643211986 bayes_pls_golite062009
  • tubulin binding
    		•  0.81703797277662 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.717730683557543 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.480348726111787 bayes_pls_golite062009
  • motor activity
    		•  0.45431702357543 bayes_pls_golite062009
  • receptor activity
    		•  0.434186339265983 bayes_pls_golite062009
  • actin binding
    		•  0.43218751822947 bayes_pls_golite062009
  • DNA binding
    		•  0.418154636457321 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.298334474872045 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.0746966011130201 bayes_pls_golite062009
  • microtubule binding
    		•  0.0655176038082335 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle