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Protein Overview: HNRNPK

General Information:
Name(s) found: HNRNPK [HGNC (HUGO)]
Description(s) found:
Found 36 descriptions.
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  • heterogeneous nuclear ribonucleoprotein K [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEQPEETF PNTETNGEFG KRPAEDMEEE QAFKRSRNTD EMVELRILLQ SKNAGAVIGK  60
   61 GGKNIKALRT DYNASVSVPD SSGPERILSI SADIETIGEI LKKIIPTLEE GLQLPSPTAT 120
  121 SQLPLESDAV ECLNYQHYKG SDFDCELRLL IHQSLAGGII GVKGAKIKEL RENTQTTIKL 180
  181 FQECCPHSTD RVVLIGGKPD RVVECIKIIL DLISESPIKG RAQPYDPNFY DETYDYGGFT 240
  241 MMFDDRRGRP VGFPMRGRGG FDRMPPGRGG RPMPPSRRDY DDMSPRRGPP PPPPGRGGRG 300
  301 GSRARNLPLP PPPPPRGGDL MAYDRRGRPG DRYDGMVGFS ADETWDSAID TWSPSEWQMA 360
  361 YEPQGGSGYD YSYAGGRGSY GDLGGPIITT QVTIPKDLAG SIIGKGGQRI KQIRHESGAS 420
  421 IKIDEPLEGS EDRIITITGT QDQIQNAQYL LQNSVKQYSG KFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] PSI-BLAST 24.154902 No description for 2annA was found.
    2 View Details [139..221] PSI-BLAST 5.154902 Solution structure of the 14th KH type I domain from human Vigilin
    3 View Details [222..309] deduced N/A No confident structure predictions are available.
    4 View Details [310..463] PSI-BLAST 15.69897 HnRNP K, KH3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  6.76415077523249 bayes_pls_golite062009
  • mRNA binding
    		•  5.07455187994216 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.68444148122352 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
    		• 2.87067043110488 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  2.05765562493656 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.43703138180882 bayes_pls_golite062009
  • DNA binding
    		•  1.20852534725468 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.981003625136521 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.489176583045793 bayes_pls_golite062009
  • transcription factor activity
    		•  0.386248501195543 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  6.76415077523249 bayes_pls_golite062009
  • mRNA binding
    		•  5.07455187994216 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.68444148122352 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
    		• 2.87067043110488 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  2.05765562493656 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.43703138180882 bayes_pls_golite062009
  • DNA binding
    		•  1.20852534725468 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.981003625136521 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.489176583045793 bayes_pls_golite062009
  • transcription factor activity
    		•  0.386248501195543 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle