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Protein Overview: QARS

General Information:
Name(s) found: QARS [HGNC (HUGO)]
Description(s) found:
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  • gi|558586|emb|CAA53600.1| glutaminyl-tRNA synthetase [Homo sapiens] [NCBI NR]
  • gi|4826960|ref|NP_005042.1| glutaminyl-tRNA synthetase [Homo sapiens] [NCBI NR]
  • pir||I37422 glutamine-tRNA ligase (EC 6.1.1.18) - human [NCBI NR]
  • gi|20987272|gb|AAH29739.1| Glutaminyl-tRNA synthetase [Homo sapiens] [NCBI NR]
  • gi|16306759|gb|AAH01567.1| Glutaminyl-tRNA synthetase [Homo sapiens] [NCBI NR]
  • gi|1351170|sp|P47897.1|SYQ_HUMAN RecName: Full=Glutaminyl-tRNA synthetase; AltName: Full=Glutamine--tRNA ligase; Short=GlnRS [NCBI NR]
  • gi|12653251|gb|AAH00394.1| Glutaminyl-tRNA synthetase [Homo sapiens] [NCBI NR]
  • glutaminyl-tRNA synthetase [HGNC (HUGO)]
  • Glutamine--tRNA ligase OS=Homo sapiens GN=QARS PE=1 SV=1 [Swiss-Prot]
  • Glutaminyl-tRNA synthetase [hmr_yeast5_DM3-1_pombe.fasta]
  • glutaminyl-tRNA synthetase; glutamine-tRNA synthetase [HMR_022704.fasta]
  • glutaminyl-tRNA synthetase [Homo sapiens]gi|16306759|gb|AAH01567.1| Glutaminyl-tRNA synthetase [Homo sapiens]gi|12653251|gb|AAH00394.1| Glutaminyl-tRNA synthetase [Homo sapiens]gi|20987272|gb|AAH29739.1| Glutaminyl-tRNA synthetase [Homo sapiens]gi|213 [nrdb_11152004_Chlamydomonas]
  • Glutaminyl-tRNA synthetase (Glutamine--tRNA ligase) (GlnRS) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Glutaminyl-tRNA synthetase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_005051) glutaminyl-tRNA synthetase; glutamine-tRNA synthetase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • glutaminyl-tRNA synthetase [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • glutaminyl-tRNA synthetase; glutamine-tRNA synthetase [Homo sapiens] [HumanGallus06162005.fasta]
  • Glutaminyl-tRNA synthetase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 GLUTAMINYL-TRNA SYNTHETASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Glutaminyl-tRNA synthetase; AltName: Full=Glutamine--tRNA ligase; Short=GlnRS [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • IPI:IPI00925046.1|SWISS-PROT:P47897|TREMBL:Q96AW5|ENSEMBL:ENSP00000307567|REFSEQ:NP_005042|H-INV:HIT000040862|VEGA:OTTHUMP00000210569 Tax_Id=9606 Gene_Symbol=QARS Glutaminyl-tRNA synthetase [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=QARS Glutaminyl-tRNA synthetase [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • Glutaminyl-tRNA synthetase OS=Homo sapiens GN=QARS PE=1 SV=1 [UniProtHuman070710.fasta]
  • P47897; RecName: Full=Glutaminyl-tRNA synthetase; AltName: Full=Glutamine--tRNA ligase; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Glutaminyl-tRNA synthetase OS=Homo sapiens GN=QARS [011711_HMR.fasta]
  • GeneSymbol=QARS Synonyms=GLNRS|PRO2195 glutaminyl-tRNA synthetase [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00925046.1|SWISS-PROT:P47897|TREMBL:A8K3A8;Q53HS0;Q96AW5|ENSEMBL:ENSP00000307567|REFSEQ:NP_005042|H-INV:HIT000040862|VEGA:OTTHUMP00000210569 Tax_Id=9606 Gene_Symbol=QARS Glutaminyl-tRNA synthetase [ipi.HUMAN.20110912.fasta]
  • Glutamine--tRNA ligase GN=QARS [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 775 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALDSLSLF TSLGLSEQKA RETLKNSALS AQLREAATQA QQTLGSTIDK ATGILLYGLA  60
   61 SRLRDTRRLS FLVSYIASKK IHTEPQLSAA LEYVRSHPLD PIDTVDFERE CGVGVIVTPE 120
  121 QIEEAVEAAI NRHRPQLLVE RYHFNMGLLM GEARAVLKWA DGKMIKNEVD MQVLHLLGPK 180
  181 LEADLEKKFK VAKARLEETD RRTAKDVVEN GETADQTLSL MEQLRGEALK FHKPGENYKT 240
  241 PGYVVTPHTM NLLKQHLEIT GGQVRTRFPP EPNGILHIGH AKAINFNFGY AKANNGICFL 300
  301 RFDDTNPEKE EAKFFTAICD MVAWLGYTPY KVTYASDYFD QLYAWAVELI RRGLAYVCHQ 360
  361 RGEELKGHNT LPSPWRDRPM EESLLLFEAM RKGKFSEGEA TLRMKLVMED GKMDPVAYRV 420
  421 KYTPHHRTGD KWCIYPTYDY THCLCDSIEH ITHSLCTKEF QARRSSYFWL CNALDVYCPV 480
  481 QWEYGRLNLH YAVVSKRKIL QLVATGAVRD WDDPRLFTLT ALRRRGFPPE AINNFCARVG 540
  541 VTVAQTTMEP HLLEACVRDV LNDTAPRAMA VLESLRVIIT NFPAAKSLDI QVPNFPADET 600
  601 KGFHQVPFAP IVFIERTDFK EEPEPGFKRL AWGQPVGLRH TGYVIELQHV VKGPSGCVES 660
  661 LEVTCRRADA GEKPKAFIHW VSQPLMCEVR LYERLFQHKN PEDPTEVPGG FLSDLNLASL 720
  721 HVVDAALVDC SVALAKPFDK FQFERLGYFS VDPDSHQGKL VFNRTVTLKE DPGKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..164] Pfam 44.200659 No description for PF04558.6 was found. No confident structure predictions are available.
    2 View Details [165..246] PSI-BLAST 10.221849 Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
    3 View Details [247..775] PSI-BLAST 171.0 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • glutamine-tRNA ligase activity
    		•  7.66556935228325 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  4.64665624411373 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.61484562096458 bayes_pls_golite062009
  • structural molecule activity
    		•  4.261982318682 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • 5S rRNA binding
    		•  2.25646775578129 bayes_pls_golite062009
  • rRNA binding
    		•  2.12571610259264 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.06535308346284 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.47302762432927 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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