Protein Overview: SLA2

General Information:
Name(s) found:	SLA2 / YNL243W [SGD]
Description(s) found: Found 13 descriptions. SHOW ALL	Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo [SGD]
Organism:	Saccharomyces cerevisiae
Length:	968 amino acids
Gene Ontology:
Cellular Component:	incipient cellular bud site [IDA] actin cortical patch [IDA]
Biological Process:	bipolar cellular bud site selection [IMP] cellular cell wall organization [IMP] telomere maintenance [IMP] actin filament organization [IMP] endocytosis [IMP] exocytosis [IMP]
Molecular Function:	protein binding, bridging [IGI][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRIDSDLQK ALKKACSVEE TAPKRKHVRA CIVYTWDHQS SKAVFTTLKT LPLANDEVQL  60
   61 FKMLIVLHKI IQEGHPSALA EAIRDRDWIR SLGRVHSGGS SYSKLIREYV RYLVLKLDFH 120
  121 AHHRGFNNGT FEYEEYVSLV SVSDPDEGYE TILDLMSLQD SLDEFSQIIF ASIQSERRNT 180
  181 ECKISALIPL IAESYGIYKF ITSMLRAMHR QLNDAEGDAA LQPLKERYEL QHARLFEFYA 240
  241 DCSSVKYLTT LVTIPKLPVD APDVFLINDV DESKEIKFKK REPSVTPART PARTPTPTPP 300
  301 VVAEPAISPR PVSQRTTSTP TGYLQTMPTG ATTGMMIPTA TGAANAIFPQ ATAQMQPDFW 360
  361 ANQQAQFANE QNRLEQERVQ QLQQQQAQQE LFQQQLQKAQ QDMMNMQLQQ QNQHQNDLIA 420
  421 LTNQYEKDQA LLQQYDQRVQ QLESEITTMD STASKQLANK DEQLTALQDQ LDVWERKYES 480
  481 LAKLYSQLRQ EHLNLLPRFK KLQLKVNSAQ ESIQKKEQLE HKLKQKDLQM AELVKDRDRA 540
  541 RLELERSINN AEADSAAATA AAETMTQDKM NPILDAILES GINTIQESVY NLDSPLSWSG 600
  601 PLTPPTFLLS LLESTSENAT EFATSFNNLI VDGLAHGDQT EVIHCVSDFS TSMATLVTNS 660
  661 KAYAVTTLPQ EQSDQILTLV KRCAREAQYF FEDLMSENLN QVGDEEKTDI VINANVDMQE 720
  721 KLQELSLAIE PLLNIQSVKS NKETNPHSEL VATADKIVKS SEHLRVDVPK PLLSLALMII 780
  781 DAVVALVKAA IQCQNEIATT TSIPLNQFYL KNSRWTEGLI SAAKAVAGAT NVLITTASKL 840
  841 ITSEDNENTS PEQFIVASKE VAASTIQLVA ASRVKTSIHS KAQDKLEHCS KDVTDACRSL 900
  901 GNHVMGMIED DHSTSQQQQP LDFTSEHTLK TAEMEQQVEI LKLEQSLSNA RKRLGEIRRH 960
  961 AYYNQDDD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: SLA2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: