Protein Overview: ENV7

General Information:
Name(s) found:	ENV7 / YPL236C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74676496\|sp\|Q12003.1\|KP236_YEAST RecName: Full=Serine/threonine-protein kinase YPL236C [NCBI NR] gi\|6325020\|ref\|NP_015088.1\| Putative protein kinase that exhibits Akr1p-dependent palmitoylation; Ypl236cp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S61028 hypothetical protein YPL236c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1370488\|emb\|CAA97954.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1061253\|emb\|CAA91608.1\| putative protein [Saccharomyces cerevisiae] [NCBI NR] Serine/threonine-protein kinase YPL236C OS=Saccharomyces cerevisiae GN=YPL236C PE=1 SV=1 [Swiss-Prot] Protein kinase localised to vacuolar membrane [mips] YPL236C SGDID:S000006157, Chr XVI from 102702-101608, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" [SGD] >Q12003 (Q12003) Chromosome XVI reading frame ORF YPL236C [4932.FASTACCERV.txt] Chr XVI from 102702-101608, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 101608-102702, reverse complement [yeastorf3.fasta] YPL236C, Chr XVI from 101608-102702, reverse complement [yeast_orfs2] YPL236C SGDID:S0006157, Chr XVI from 102702-101608, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Ypl236cp [Saccharomyces cerevisiae]gi\|1370488\|emb\|CAA97954.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1061253\|emb\|CAA91608.1\| putative protein [Saccharomyces cerevisiae]gi\|2132243\|pir\|\|S61028 hypothetical protein YPL236c - yeast (Saccharom [nrdb_11152004_Chlamydomonas] (Q12003) S.cerevisiae chromosome XVI reading frame ORF YPL236c (Hypothetical protein) [cerv4932.FASTAC] YPL236C SGDID:S000006157, Chr XVI from 102702-101608, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YPL236C SGDID:S000006157, Chr XVI from 102702-101608, reverse complement, Uncharacterized ORF, "Putative protein kinase that exhibits Akr1p-dependent palmitoylation" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] YPL236C SGDID:S000006157, Chr XVI from 102702-101608, reverse complement, Uncharacterized ORF [yeast-200209-contam.fasta] hypothetical protein; Ypl236cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] putative protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Serine/threonine-protein kinase YPL236C [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Serine/threonine-protein kinase ENV7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENV7 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] ENV7 SGDID:S000006157, Chr XVI from 102702-101608, Genome Release 64-2-1, reverse complement, Verified ORF, "Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16)" [20141208_orf_trans.fasta] TR8663\|c0_g1_i1\|g.6126 ORF TR8663\|c0_g1_i1\|g.6126 TR8663\|c0_g1_i1\|m.6126 type:complete len:365 (+) TR8663\|c0_g1_i1:271-1365(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] asmbl_3012\|g.2169 ORF asmbl_3012\|g.2169 asmbl_3012\|m.2169 type:complete len:365 (+) asmbl_3012:270-1364(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_3412\|g.1899 ORF ID=asmbl_3412\|g.1899 ID=asmbl_3412\|m.1899 type:complete len:365 (+) ID=asmbl_3412:270-1364(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	364 amino acids
Gene Ontology:
Cellular Component:	fungal-type vacuole membrane [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	protein serine/threonine kinase activity [ISS ]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISIVLELFQ NLCCCRGFSD ATIRVNDKRY RIQRLLGEGG MSFVYLVQLS KNSLIIDNGI  60
   61 ATPELYALKK IICPSVESIS NGMREIENYK RFQSPYVIKS IDSQVMQEKD GSKTIYIVLP 120
  121 YYSLGSLQDS INRRLLEGTF VSEAECVRIM LGVTRGLLCL HDPASRQDNA TSRVNVDAVS 180
  181 MTYSDETAML LEDTPLEMDM LSSNSAGSIA YAHRDITPSN ILFSSDGLPV IGDLGSCSQA 240
  241 DITIENRHQL SELQEWVNDN CTLPYTPPEL LNLKLNQVLS SKVDIWSLGC TFYTLMFGIS 300
  301 PFEREEQIHG ASLTYAINTG KYSFPRNSRF SEGLLSVIKK CIQVDPIQRP TTSQLLNLLQ 360
  361 DLDT

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		ENV7 UFD2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YJL147C	ENV7	2	Unpublished Fields Lab Data
View Screen	EUG1	ENV7	1	Unpublished Fields Lab Data
View Screen	YPT35	ENV7	1	Unpublished Fields Lab Data
View Screen	UBC7	ENV7	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	ENV7	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..121]	PSI-BLAST	138.0	Aurora-related kinase 1 (aurora-2)
2	View Details	[122..364]	PSI-BLAST	138.0	Aurora-related kinase 1 (aurora-2)

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2