Protein Overview: BTS1

General Information:
Name(s) found:	BTS1 / YPL069C [SGD]
Description(s) found: Found 29 descriptions. SHOW ALL	Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic [SGD]
Organism:	Saccharomyces cerevisiae
Length:	335 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA]
Biological Process:	terpenoid biosynthetic process [IDA][IGI][IMP]
Molecular Function:	farnesyltranstransferase activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAKIDELIN NDPVWSSQNE SLISKPYNHI LLKPGKNFRL NLIVQINRVM NLPKDQLAIV  60
   61 SQIVELLHNS SLLIDDIEDN APLRRGQTTS HLIFGVPSTI NTANYMYFRA MQLVSQLTTK 120
  121 EPLYHNLITI FNEELINLHR GQGLDIYWRD FLPEIIPTQE MYLNMVMNKT GGLFRLTLRL 180
  181 MEALSPSSHH GHSLVPFINL LGIIYQIRDD YLNLKDFQMS SEKGFAEDIT EGKLSFPIVH 240
  241 ALNFTKTKGQ TEQHNEILRI LLLRTSDKDI KLKLIQILEF DTNSLAYTKN FINQLVNMIK 300
  301 NDNENKYLPD LASHSDTATN LHDELLYIID HLSEL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YPT53	BTS1	1	Unpublished Fields Lab Data
View Screen	APC5	BTS1	1	Unpublished Fields Lab Data
View Screen	GBP2	BTS1	1	Unpublished Fields Lab Data
View Screen	YCK1	BTS1	1	Unpublished Fields Lab Data
View Screen	CDC23	BTS1	1	Unpublished Fields Lab Data
View Screen	PSF2	BTS1	1	Hazbun TR, et al. (2003)
View Screen	PRP40	BTS1	1	Unpublished Fields Lab Data
View Screen	TEM1	BTS1	1	Unpublished Fields Lab Data
View Screen	HMG1	BTS1	1	Unpublished Fields Lab Data
View Screen	HMG1	BTS1	1	Unpublished Fields Lab Data
View Screen	RRB1	BTS1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	BTS1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..143] [167..191]	PSI-BLAST	117.917458	Farnesyl diphosphate synthase
2	View Details	[144..166] [192..335]	PSI-BLAST	117.917458	Farnesyl diphosphate synthase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2