Protein Overview: CWC27

General Information:
Name(s) found:	CWC27 / YPL064C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|73918950\|sp\|Q02770.1\|CWC27_YEAST RecName: Full=Peptidyl-prolyl isomerase CWC27; AltName: Full=Complexed with CEF1 protein 27 [NCBI NR] gi\|6325193\|ref\|NP_015261.1\| Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p; Cwc27p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S60926 hypothetical protein YPL064c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1079678\|gb\|AAB68301.1\| Ypl064cp [Saccharomyces cerevisiae] [NCBI NR] Peptidyl-prolyl isomerase CWC27 OS=Saccharomyces cerevisiae GN=CWC27 PE=1 SV=1 [Swiss-Prot] CWC27 Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing [mips] Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p [SGD] >Q02770 (Q02770) LPE6P [4932.FASTACCERV.txt] Chr XVI from 429611-428706, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 428706-429611, reverse complement [yeastorf3.fasta] YPL064C, Chr XVI from 428706-429611, reverse complement [yeast_orfs2] CWC27 SGDID:S0005985, Chr XVI from 429611-428706, reverse complement, Verified ORF [yeastflysequest.fasta] CWC27 SGDID:S0005985, Chr XVI from 429613-428708, reverse complement, Verified ORF [10112005cervSGD.fasta] Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p [Saccharomyces cerevisiae]gi\|2132172\|pir\|\|S60926 hypothetical protein YPL064c - yeast (Saccharomyces cerevisiae)gi\|1079678\|gb\|AAB68301.1 [nrdb_11152004_Chlamydomonas] (Q02770) Ypl064cp [cerv4932.FASTAC] CWC27 SGDID:S000005985, Chr XVI from 429613-428708, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p; Cwc27p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Peptidyl-prolyl isomerase CWC27 (Complexed with CEF1 protein 27) [nr-271106-contam.fasta] Ypl064cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Peptidyl-prolyl isomerase CWC27 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CWC27 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] CWC27 SGDID:S000005985, Chr XVI from 429616-428711, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p" [yeast-030211-contam.fasta] CWC27 SGDID:S000005985, Chr XVI from 429616-428711, Genome Release 64-2-1, reverse complement, Verified ORF, "Component of a complex containing Cef1p; putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta] YPL064C SGDID:S000005985, Chr XVI from 429616-428711, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	301 amino acids
Gene Ontology:
Cellular Component:	spliceosomal complex [IPI]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNIEPQTT AKCILYTTKG NIAIELWAKE CPETCKRFLS MLSDGTFTNG EFKELKPTQW  60
   61 LMFNANSTGE YRTVAEEKNP RIRFNRDGLL GWDRRRNTWF ITVLADSKHV LNDCNVFGKI 120
  121 VGKSIYIFRE ILGGEIEASS RDNDVKRFMY PAVLKDVEIT IPFFEDIFGS KRRLEDNEKK 180
  181 EQEPAKKLVK SAKVKMVYED EQEDDDGDVQ KLKPRKRMIL PAWIKDDSRS EGIKLDASLD 240
  241 QPQEALIREK TELHDNVDEA TTKETESQEN IKEEPMDKRE RETLAMLSKF QERIKNKNIL 300
  301 K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MET18	CWC27	2	Unpublished Fields Lab Data
View Screen	NUC1	CWC27	1	Unpublished Fields Lab Data
View Screen	YLR224W	CWC27	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	CWC27	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..197]	PSI-BLAST	63.69897	Cyclophilin (eukaryotic)
2	View Details	[198..301]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
catalytic activity	0.748655649755714	bayes_pls_golite062009
binding	0.508724818609046	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2