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Protein Overview: HSP33

General Information:
Name(s) found: HSP33 / YOR391C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: cysteine-type peptidase activity [ISSLink to PubMed article]
    unfolded protein binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPKRALISL TSYHGPFYKD GAKTGVFVVE ILRSFDTFEK HGFEVDFVSE TGGFGWDEHY  60
   61 LPKSFIGGED KMNFETKNSA FNKALARIKT ANEVNASDYK VFFASAGHGA LFDYPKAKNL 120
  121 QDIASKIYAN GGVIAAICHG PLLFDGLIDI KTTRPLIEGK AITGFPLEGE IALGVDDILR 180
  181 SRKLTTVERV ANKNGAKYLA PIHPWDDYSI TDGKLVTGVN ANSSYSTTIR AINALYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HSP33 AIM37 2 Unpublished Fields Lab Data
    View Screen HSP33 HSP32 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..237] PSI-BLAST 61.0 HSP31 (HchA; YedU)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.761311388604334 bayes_pls_golite062009
  • binding
    		•  0.674707430307546 bayes_pls_golite062009
  • ligase activity
    		•  0.314215307503825 bayes_pls_golite062009
  • hydrolase activity
    		•  0.132707384514464 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle