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Protein Overview: HNT3

General Information:
Name(s) found: HNT3 / YOR258W [SGD]
Description(s) found:
Found 26 descriptions.
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  • DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 217 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWRYALKNY VTSPETVNDD TVTYFDDKVS IIRDSFPKSE CHLLILPRTM QLSRSHPTKV  60
   61 IDAKFKNEFE SYVNSAIDHI FRHFQEKFRI KKSDDDKDPC WDDILKDKNK FVRNFVQVGI 120
  121 HSVPSMANLH IHVISKDFHS VRLKNKKHYN SFNTGFFISW DDLPLNGKNL GTDKEIETTY 180
  181 LKEHDLLCCY CQRNFSNKFS LLKKHLELEF NSHFELK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data HNT3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] ORFEUS 9.62 Protein kinase C inhibitor-1, PKCI-1
    2 View Details [162..217] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.15228990656368 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.73265651460534 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.631037396994785 bayes_pls_golite062009
  • transferase activity
    		•  0.405724480958777 bayes_pls_golite062009
  • catalytic activity
    		•  0.128210794769743 bayes_pls_golite062009
  • protein binding
    		•  0.0801073049129787 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle