Protein Overview: NAT5

General Information:
Name(s) found:	NAT5 / YOR253W [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing [SGD]
Organism:	Saccharomyces cerevisiae
Length:	176 amino acids
Gene Ontology:
Cellular Component:	NatA complex [IDA]
Biological Process:	N-terminal protein amino acid acetylation [IC][ISS]
Molecular Function:	peptide alpha-N-acetyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRDICTLDN VYANNLGMLT KLAHVTVPNL YQDAFFSALF AEDSLVAKNK KPSSKKDVHF  60
   61 TQMAYYSEIP VGGLVAKLVP KKQNELSLKG IQIEFLGVLP NYRHKSIGSK LLKFAEDKCS 120
  121 ECHQHNVFVY LPAVDDLTKQ WFIAHGFEQV GETVNNFIKG VNGDEQDAIL LKKHIS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ARD1 NAT1 NAT5
View Details	Krogan NJ, et al. (2006)		ARD1 NAT1 NAT5 RIM8
View Details	Qiu et al. (2008)		ARD1 MAK10 MAK3 MAK31 MDM20 NAT1 NAT3 NAT5

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NTA1	NAT5	1	Unpublished Fields Lab Data
View Screen	SNF4	NAT5	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	NAT5	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..176]	PSI-BLAST	14.69897	Aminoglycoside 3-N-acetyltransferase

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
N-acetyltransferase activity	6.19030807112666	bayes_pls_golite062009
N-acyltransferase activity	6.08913516066746	bayes_pls_golite062009
histone acetyltransferase activity	6.0067454358666	bayes_pls_golite062009
lysine N-acetyltransferase activity	6.0067454358666	bayes_pls_golite062009
acetyltransferase activity	5.86411968036951	bayes_pls_golite062009
acyltransferase activity	4.72881921515185	bayes_pls_golite062009
transferase activity, transferring acyl groups	4.70793039001114	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	4.69837915971204	bayes_pls_golite062009
transferase activity	3.5778020729894	bayes_pls_golite062009
glycylpeptide N-tetradecanoyltransferase activity	3.50779447340192	bayes_pls_golite062009
myristoyltransferase activity	3.50779447340192	bayes_pls_golite062009
	3.29707445389818	bayes_pls_golite062009
catalytic activity	1.97933499002461	bayes_pls_golite062009
binding	0.203201636645541	bayes_pls_golite062009
protein binding	0.0596470189462109	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2