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Protein Overview: DDP1

General Information:
Name(s) found: DDP1 / YOR163W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 188 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: diadenosine polyphosphate metabolic process [IDALink to PubMed article]
    Molecular Function: diphosphoinositol-polyphosphate diphosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKTADNHGP VRSETAREGR ENQVYSPVTG ARLVAGCICL TPDKKQVLMI TSSAHKKRWI  60
   61 VPKGGVEKDE PNYETTAQRE TWEEAGCIGK IVANLGTVED MRPPKDWNKD IKQFENSRKD 120
  121 SEVAKHPPRT EFHFYELEIE NLLDKFPECH KRHRKLYSYT EAKQNLIDAK RPELLEALNR 180
  181 SAIIKDDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data DDP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] PSI-BLAST 21.09691 Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.49075808737475 bayes_pls_golite062009
  • hydrolase activity
    		•  1.08437985755037 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.654571025500586 bayes_pls_golite062009
  • binding
    		•  0.648929968265004 bayes_pls_golite062009
  • transferase activity
    		•  0.338414890259504 bayes_pls_golite062009
  • protein binding
    		•  0.0607475466763231 bayes_pls_golite062009
  • bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
    		•  0.0140979802606357 bayes_pls_golite062009
  • bis(5'-nucleosyl)-tetraphosphatase activity
    		•  0.0140979802606357 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle