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Protein Overview: RIO1

General Information:
Name(s) found: RIO1 / YOR119C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 484 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: S phase of mitotic cell cycle [IDALink to PubMed article]
    maturation of SSU-rRNA [IDALink to PubMed articleLink to PubMed article]
    regulation of exit from mitosis [IDALink to PubMed article]
    Molecular Function: protein kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEDKFDSL SVSQGASDHI NNQLLEKYSH KIKTDELSFS RAKTSKDKAN RATVENVLDP  60
   61 RTMRFLKSMV TRGVIADLNG CLSTGKEANV YHAFAGTGKA PVIDEETGQY EVLETDGSRA 120
  121 EYAIKIYKTS ILVFKDRERY VDGEFRFRNS RSQHNPRKMI KIWAEKEFRN LKRIYQSGVI 180
  181 PAPKPIEVKN NVLVMEFLSR GNGFASPKLK DYPYKNRDEI FHYYHTMVAY MRLLYQVCRL 240
  241 VHADLSEYNT IVHDDKLYMI DVSQSVEPEH PMSLDFLRMD IKNVNLYFEK MGISIFPERV 300
  301 IFQFVISETL EKFKGDYNNI SALVAYIASN LPIKSTEQDE AEDEIFRSLH LVRSLGGLEE 360
  361 RDFDRYTDGK FDLLKSLIAH DNERNFAASE QFEFDNADHE CSSGTEEFSD DEEDGSSGSE 420
  421 EDDEEEGEYY DDDEPKVLKG KKHEDKDLKK LRKQEAKDAK REKRKTKVKK HIKKKLVKKT 480
  481 KSKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 14.69897 c-src protein tyrosine kinase; c-src tyrosine kinase
    2 View Details [104..200] PSI-BLAST 45.0 Calmodulin-dependent protein kinase
    3 View Details [201..417] PSI-BLAST 45.0 Calmodulin-dependent protein kinase
    4 View Details [418..484] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle