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Protein Overview: OST3

General Information:
Name(s) found: OST3 / YOR085W [SGD]
Description(s) found:
Found 34 descriptions.
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  • Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 350 amino acids

    Gene Ontology:
    Cellular Component: oligosaccharyltransferase complex [IPILink to PubMed articleLink to PubMed articleLink to PubMed article]
    integral to membrane [IMPLink to PubMed article]
    Biological Process: protein complex assembly [IMPLink to PubMed article]
    protein amino acid glycosylation [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IPILink to PubMed article]
    Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity [IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNWLFLVSLV FFCGVSTHPA LAMSSNRLLK LANKSPKKII PLKDSSFENI LAPPHENAYI  60
   61 VALFTATAPE IGCSLCLELE SEYDTIVASW FDDHPDAKSS NSDTSIFFTK VNLEDPSKTI 120
  121 PKAFQFFQLN NVPRLFIFKP NSPSILDHSV ISISTDTGSE RMKQIIQAIK QFSQVNDFSL 180
  181 HLPMDWTPII TSTIITFITV LLFKKQSKLM FSIISSRIIW ATLSTFFIIC MISAYMFNQI 240
  241 RNTQLAGVGP KGEVMYFLPN EFQHQFAIET QVMVLIYGTL AALVVVLVKG IQFLRSHLYP 300
  301 ETKKAYFIDA ILASFCALFI YVFFAALTTV FTIKSPAYPF PLLRLSAPFK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) OST1 OST2 OST3 OST4 OST5 OST6 STT3 SWP1 WBP1
    View Details Qiu et al. (2008) OST1 OST2 OST3 OST4 OST5 OST6 STT3 SWP1 WBP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data OST3 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] MSA 1.014987 View MSA. No confident structure predictions are available.
    2 View Details [96..350] MSA 2.015948 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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