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Protein Overview: WSC3

General Information:
Name(s) found: WSC3 / YOL105C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 556 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [ISSLink to PubMed article]
    Biological Process: response to heat [IGILink to PubMed article][ISSLink to PubMed article]
    cellular cell wall organization [TASLink to PubMed article]
    Rho protein signal transduction [IGILink to PubMed article][ISSLink to PubMed article]
    actin cytoskeleton organization [TASLink to PubMed article]
    Molecular Function: transmembrane receptor activity [IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERVWFAKLT NKGTIKIGYI SFILLSLLCQ SLIGLVNADF NYEGCYSAAD IQSAGLSLKN  60
   61 SYIYQSVSYC QNQCPESAVV ALFNGSDCYC GNSVSFLTSL TKSTDSNCGT KCSGWPYQMC 120
  121 GGSSYMNVYV NAETFVSSVE SSSSKEGSST SYMPSTTSSL SSAQISSTTR RTSTDMKSSE 180
  181 MIATTVSTTS TTSSSTSSTT SSTTSSTTSS TTSSTTSSST SSTTSSTTSS TTSSTTSSTT 240
  241 SSTTSSTTSS TTSSTTSIFS VTSSSSSITL SSSEHTTVDS RTSSPSSTLV PVSSSSSTLS 300
  301 TPKVTSMTPS TSSTIPIVTS VELVTSVVTK AIVSTSDQHQ ETIFVTRTSV VERSSEVATA 360
  361 TAAASNNRSN STSKQRLSGG AIAGIVIGVV FGVIFIILIL LFLIWRRRKS HDQLDLEETK 420
  421 HYQPYSFGDE DANPIGPPPS SGTTNWMRHS RGNTAGSIGT SNMYGFSMSN GANYSSPSSN 480
  481 TSGSIINNLA GLQDATVQKQ NLPSTVFEEA NTLNSANERF SANSLPDMMM SGPLQVVNPD 540
  541 NPDNPELSST VSHNRA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) SLG1 WSC2 WSC3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data WSC3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] Pfam 22.251812 WSC domain No confident structure predictions are available.
    2 View Details [113..173] ORFEUS 11.96 Fibrinogen
    3 View Details [174..475] ORFEUS 12.06 Fibrinogen
    4 View Details [476..556] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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