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Protein Overview: ZRG17

General Information:
Name(s) found: ZRG17 / YNR039C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 605 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: zinc ion transport [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METPQMNAIQ EEDNLSPEVA FQTPKLNDSD ASSFSLSNMN AVGNVDGIPS QNRTFFASPR  60
   61 PSSLFYSAKE GNNSSSSIIY NPSFTFGENA SSNANINEAA LMKGKGNEGR RQSLKYIPAP 120
  121 KLVPPPPRTR SPVRGISPDA GSSKRSSMTL DSPFNFTTST LQPHQQTPPS SAASRTSFRK 180
  181 GHRYKHSSVS MNFFQEPEVK IPLNIAKSLP IPDFNDLLSN LPWPKAYIQL SIAALQIFAC 240
  241 LITFQVGHLY SWSNFITLSH FITYDIIGSL VIIFVENLSQ FQVWFTGTIT FPFGLNRIDV 300
  301 LLSFALAVSL CFVGLDLLFH IIEEFIVLFV ESGSSLTNNH DHDEINEQIP HSHIANANDS 360
  361 QNENITLWYS ILMINLVLST LSLYKTFYAN KYSNLKTKNP IITITYTAYL FIYPLLLDLL 420
  421 SSISDYLATL VISSLILWHG LTIARWTSTV LLMGFSTTSL SNSALFNNND STDTTAHTQQ 480
  481 VESKAAKEKP SVRPRSMSSL PIATKNTKIR KTGFLNSAGF TENPTTIKNM IKDQIERLSE 540
  541 FKSRYILNYD DIVISKVNFT LYVVLIKITM KGGSDDDELM LRLAIDKCIQ TSIPTCETTI 600
  601 DIDRI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) MED4 ZRG17

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PGA1 ZRG17 2 Unpublished Fields Lab Data
    View Screen YIF1 ZRG17 2 Unpublished Fields Lab Data
    View Screen PHS1 ZRG17 2 Unpublished Fields Lab Data
    View Screen GPI14 ZRG17 2 Hazbun TR, et al. (2003)
    View Screen YNL146W ZRG17 2 Unpublished Fields Lab Data
    View Screen SEC17 ZRG17 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ZRG17 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..137] deduced N/A No confident structure predictions are available.
    2 View Details [138..356] MSA 1.002914 View MSA. No confident structure predictions are available.
    3 View Details [357..605] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • cation transmembrane transporter activity
    		•  4.66797577217092 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.59426322530417 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.22757882358966 bayes_pls_golite062009
  • transporter activity
    		•  2.72875628342635 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.5812016552653 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.42221734489039 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  1.51622356320367 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.20045998574251 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.06864285262933 bayes_pls_golite062009
  • binding
    		•  1.0333257243016 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.683534503198654 bayes_pls_golite062009
  • efflux transmembrane transporter activity
    		•  0.556703621451116 bayes_pls_golite062009
  • cation channel activity
    		•  0.258076515880771 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  0.186398867523746 bayes_pls_golite062009
  • protein binding
    		•  0.0991944030928594 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle