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Protein Overview: ABZ1

General Information:
Name(s) found: ABZ1 / YNR033W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 787 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: para-aminobenzoic acid metabolic process [IMPLink to PubMed article]
    Molecular Function: 4-amino-4-deoxychorismate synthase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSDTIDTKQ QQQQLHVLFI DSYDSFTYNV VRLIEQQTDI SPGVNAVHVT TVHSDTFQSM  60
   61 DQLLPLLPLF DAIVVGPGPG NPNNGAQDMG IISELFENAN GKLDEVPILG ICLGFQAMCL 120
  121 AQGADVSELN TIKHGQVYEM HLNDAARACG LFSGYPDTFK STRYHSLHVN AEGIDTLLPL 180
  181 CTTEDENGIL LMSAQTKNKP WFGVQYHPES CCSELGGLLV SNFLKLSFIN NVKTGRWEKK 240
  241 KLNGEFSDIL SRLDRTIDRD PIYKVKEKYP KGEDTTYVKQ FEVSEDPKLT FEICNIIREE 300
  301 KFVMSSSVIS ENTGEWSIIA LPNSASQVFT HYGAMKKTTV HYWQDSEISY TLLKKCLDGQ 360
  361 DSDLPGSLEV IHEDKSQFWI TLGKFMENKI IDNHREIPFI GGLVGILGYE IGQYIACGRC 420
  421 NDDENSLVPD AKLVFINNSI VINHKQGKLY CISLDNTFPV ALEQSLRDSF VRKKNIKQSL 480
  481 SWPKYLPEEI DFIITMPDKL DYAKAFKKCQ DYMHKGDSYE MCLTTQTKVV PSAVIEPWRI 540
  541 FQTLVQRNPA PFSSFFEFKD IIPRQDETPP VLCFLSTSPE RFLKWDADTC ELRPIKGTVK 600
  601 KGPQMNLAKA TRILKTPKEF GENLMILDLI RNDLYELVPD VRVEEFMSVQ EYATVYQLVS 660
  661 VVKAHGLTSA SKKTRYSGID VLKHSLPPGS MTGAPKKITV QLLQDKIESK LNKHVNGGAR 720
  721 GVYSGVTGYW SVNSNGDWSV NIRCMYSYNG GTSWQLGAGG AITVLSTLDG ELEEMYNKLE 780
  781 SNLQIFM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ABZ1 MPA43 TSA1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ABZ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..249] PSI-BLAST 257.855515 Anthranilate synthase GAT subunit, TrpG
    2 View Details [250..787] PSI-BLAST 481.457575 P-aminobenzoate synthase component I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • anthranilate synthase activity
    		•  9.07528926783927 bayes_pls_golite062009
  • oxo-acid-lyase activity
    		•  7.16633518631507 bayes_pls_golite062009
  • 4-amino-4-deoxychorismate synthase activity
    		•  4.48164623771604 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  4.14261580175621 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.7339517212315 bayes_pls_golite062009
  • ligase activity
    		•  1.70348758031146 bayes_pls_golite062009
  • catalytic activity
    		•  1.30391542469987 bayes_pls_golite062009
  • binding
    		•  1.22860407524238 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.01721974200042 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.774587372455935 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.628648036096965 bayes_pls_golite062009
  • imidazoleglycerol-phosphate synthase activity
    		•  0.270391651600004 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.0769356405014503 bayes_pls_golite062009
  • protein binding
    		•  0.0152024556625711 bayes_pls_golite062009
    2
    Term Confidence Notes
  • anthranilate synthase activity
    		•  11.4918303265177 bayes_pls_golite062009
  • 4-amino-4-deoxychorismate synthase activity
    		•  9.91522831720207 bayes_pls_golite062009
  • oxo-acid-lyase activity
    		•  9.57649905871948 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  2.42362294309332 bayes_pls_golite062009
  • catalytic activity
    		•  2.11110806828104 bayes_pls_golite062009
  • binding
    		•  1.73874372115438 bayes_pls_golite062009
  • lyase activity
    		•  0.454734323696838 bayes_pls_golite062009
  • protein binding
    		•  0.323833479841771 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle