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Protein Overview: VNX1

General Information:
Name(s) found: VNX1 / YNL321W [SGD]
Description(s) found:
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  • gi|633664|emb|CAA86376.1| NO339 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6324008|ref|NP_014078.1| Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate; Vnx1p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1302434|emb|CAA96252.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1176583|sp|P42839.1|VNX1_YEAST RecName: Full=Low affinity vacuolar monovalent cation/H(+) antiporter; AltName: Full=Vacuolar Na(+)/H(+) exchanger [NCBI NR]
  • pir||S51293 probable membrane protein YNL321w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Putative cation exchanger YNL321W OS=Saccharomyces cerevisiae GN=YNL321W PE=1 SV=1 [Swiss-Prot]
  • Low affinity vacuolar monovalent cation/H(+) antiporter OS=Saccharomyces cerevisiae GN=VNX1 PE=1 SV=1 [Swiss-Prot]
  • Member of Ca++/H+ Antiporter family [mips]
  • Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate [SGD]
  • Chr XIV from 34695-37421 [yeastorf5.fasta]
  • (P42839) Hypothetical 102.5 kDa protein in KRE1-HXT14 intergenic region [4932.FASTACCERV.txt]
  • YNL321W, Chr XIV from 34695-37421 [yeast_orfs2]
  • YNL321W SGDID:S0005265, Chr XIV from 34695-37421, Uncharacterized ORF [yeastflysequest.fasta]
  • Protein of unknown function, potential Cdc28p substrate [Saccharomyces cerevisiae]gi|1302434|emb|CAA96252.1| unnamed protein product [Saccharomyces cerevisiae]gi|1077426|pir||S51293 probable membrane protein YNL321w - yeast (Saccharomyces cerevisiae)gi [nrdb_11152004_Chlamydomonas]
  • YNL321W SGDID:S000005265, Chr XIV from 34695-37421, Uncharacterized ORF, "Protein of unknown function, potential Cdc28p substrate" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • VNX1 SGDID:S000005265, Chr XIV from 34695-37421, Verified ORF, "Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Putative cation exchanger YNL321W [nr-271106-contam.fasta]
  • Protein of unknown function, potential Cdc28p substrate; Ynl321wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • NO339 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Low affinity vacuolar monovalent cation/H(+) antiporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VNX1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • VNX1 SGDID:S000005265, Chr XIV from 34696-37422, Genome Release 64-1-1, Verified ORF, "Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate" [yeast-030211-contam.fasta]
  • VNX1 SGDID:S000005265, Chr XIV from 34696-37422, Genome Release 64-2-1, Verified ORF, "Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate" [20141208_orf_trans.fasta]
  • YNL321W SGDID:S000005265, Chr XIV from 34696-37422, Genome Release 64-1-1, Verified ORF, "Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 908 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKNNHISAS GNSTSGDHRL KEEVLTPTTS ASTPHRIFSV DDDPKEIQND IRYLEGLHEG  60
   61 LKFALHANKS KRSVSSQSPI VHSSNNTLHH HEHQQHLPPT LESLSSKSHS VPDLNTATPS 120
  121 SPKRMHSSIR ELPHDDNDDE DANDDSRFII HDSHGHDLLI DEINCQSPSH LENNDQASNA 180
  181 SSTESFTLRE RQDAINETHP FGIRIWKPAL YKKHRSVQRT AAQDIHETQL KTITWEVTCS 240
  241 NVLWFILFGF PIAILFYSAA IVVFLLGGGG LVTNSAKEYS KCLYKLANYF LWPFGKMVYL 300
  301 LQDEQYLQED KDEGISMQQF YNWVTSYSNR LVFHQSQAKF QQREDHPAPA TESSSLMPPA 360
  361 NTTATPLNSN HPSYNSIRHE IPHAAAQRRY FGRGKWSWGR VLFYTIFHLV LQPILAVLSL 420
  421 CLWLLVFTIP MSNVLWQIMY HCRRHPLALG FKYVENSSQS HENEITQQQL NKNILLCTFR 480
  481 AAGWHYYKYT VDGTNVIVVN LISIVFFTIF DFYVLKNFLH WKTWFTYESS IFILCLTSTI 540
  541 PLAFYIGQAV ASISAQTSMG VGAVINAFFS TIVEIFLYCV ALQQKKGLLV EGSMIGSILG 600
  601 AVLLLPGLSM CGGALNRKTQ RYNPASAGVS SALLIFSMIV MFVPTVLYEI YGGYSVNCAD 660
  661 GANDRDCTFS HPPLKFNRLF THVIQPMSIS CAIVLFCAYI IGLWFTLRTH AKMIWQLPIA 720
  721 DPTSTAPEQQ EQNSHDAPNW SRSKSTCILL MSTLLYAIIA EILVSCVDAV LEDIPSLNPK 780
  781 FLGLTIFALI PNTTEFLNAI SFAIHGNVAL SMEIGSAYAL QVCLLQIPSL VIYSIFYTWN 840
  841 VKKSMINIRT QMFPLVFPRW DIFGAMTSVF MFTYLYAEGK SNYFKGSMLI LLYIIIVVGF 900
  901 YFQGALSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run VAM3 hx21: both fusion and trans-SNARE complex formation take place. Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] deduced N/A No confident structure predictions are available.
    2 View Details [179..326] Pfam 32.187087 Domain of unknown function (DUF307) No confident structure predictions are available.
    3 View Details [327..464] deduced N/A No confident structure predictions are available.
    4 View Details [465..908] MSA 41.116994 View MSA. No confident structure predictions are available.
    5 View Details [720..908] Pfam 20.769551 No description for PF01699.15 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle