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Protein Overview: MPA43

General Information:
Name(s) found: MPA43 / YNL249C [SGD]
Description(s) found:
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  • gi|6324080|ref|NP_014150.1| Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Mpa43p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|51830504|gb|AAU09778.1| YNL249C [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S63222 MPA43 protein - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1709083|sp|P53583.1|MPA43_YEAST RecName: Full=Protein MPA43 [NCBI NR]
  • gi|1302291|emb|CAA96156.1| MPA43 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1255969|emb|CAA65495.1| MPA43 [Saccharomyces cerevisiae] [NCBI NR]
  • Protein MPA43 OS=Saccharomyces cerevisiae GN=MPA43 PE=1 SV=1 [Swiss-Prot]
  • (P53583) MPA43 protein [Swiss-Prot]
  • MPA43 Mitochondrial protein of unknown function [mips]
  • Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
  • Chr XIV from 179393-181021, reverse complement [yeastorf3.fasta]
  • Chr XIV from 181021-179393, reverse complement [yeastorf5.fasta]
  • MPA43, Chr XIV from 179393-181021, reverse complement [yeast_orfs2]
  • MPA43 SGDID:S0005193, Chr XIV from 181021-179393, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Mitochondrial protein of unknown function [Saccharomyces cerevisiae]gi|51830504|gb|AAU09778.1| YNL249C [Saccharomyces cerevisiae]gi|1255969|emb|CAA65495.1| MPA43 [Saccharomyces cerevisiae]gi|1302291|emb|CAA96156.1| MPA43 [Saccharomyces cerevisiae]gi|2 [nrdb_11152004_Chlamydomonas]
  • MPA43 SGDID:S000005193, Chr XIV from 181023-179395, reverse complement, Verified ORF, "Mitochondrial protein of unknown function" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • MPA43 SGDID:S000005193, Chr XIV from 181023-179395, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • YNL249C [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • MPA43 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein MPA43 [nr-271106-contam.fasta]
  • Mitochondrial protein of unknown function; Mpa43p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Protein MPA43 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPA43 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • MPA43 SGDID:S000005193, Chr XIV from 181022-179394, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [yeast-030211-contam.fasta]
  • MPA43 SGDID:S000005193, Chr XIV from 181022-179394, Genome Release 64-2-1, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [20141208_orf_trans.fasta]
  • YNL249C SGDID:S000005193, Chr XIV from 181022-179394, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 542 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSSLQVGIG IDVGSSSARI GVYNYYNDAL LEMAQEPVPY YQDSSKKSWK FWQKSTEIIK  60
   61 ALQKCLQKLN IREYEVKSCG VSATCSLAIF ERDRTSNMLI PYPNEDNVIF WMDSSAVNEC 120
  121 QWLNMQCPQQ LLDYLGGKFV PEMGVPKLKY FLDEYSHLRD KHFHIFDLHQ YIAYELSRLY 180
  181 EWNIEGLLGR ENLNGIGNDG EVSGWSSSFY KNIINLPSNV SIGTTSLVAN KHISTTVVRS 240
  241 CIDSYASWFA VASPHLETSL FMIAGTSSCY MYGTTISDTR IPGVWGPFDT ILDNRGDFSV 300
  301 YAAGQSCTGK LIEHLFESHP CARKILKDGA DIYQVLEQTI RDIEKNNGLS IHILTKDMFF 360
  361 YGDYEGNRTP FADPRIKGSF IGESTDTSML NLTYKYICIL EFLSFQTKLI IDTFQNENSN 420
  421 IHIKELRISG SQAKNERLLS LISLVNNGVA IIKPKENVDM MGIKGAYVLA KSAKEKKQLA 480
  481 DVITERDISN DSEKFESLAE YRLGNDSILL RKLLCVKYHI HLDMAKQQKR YHKLVDEVFQ 540
  541 HL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ABZ1 MPA43 TSA1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 126.0 Glycerol kinase
    2 View Details [265..313]
    [457..487]    		 PSI-BLAST 126.0 Glycerol kinase
    3 View Details [314..456]
    [488..542]    		 PSI-BLAST 126.0 Glycerol kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.49074335090904 bayes_pls_golite062009
  • protein binding
    		•  0.856838411407636 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.0904842102388556 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle