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Protein Overview: GIM3

General Information:
Name(s) found: GIM3 / YNL153C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 129 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    prefoldin complex [IPILink to PubMed article][ISSLink to PubMed article]
    Biological Process: tubulin complex assembly [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: tubulin binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELLPQGQRN NTQVTFEDQQ KINEFSKLIM RKDAIAQELS LQREEKEYLD DVSLEIELID  60
   61 EDEPVQYKVG DLFIFMKQSK VTAQLEKDAE RLDNKIETLE DKQRDIDSRL DALKAILYAK 120
  121 FGDNINLER

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GIM3 GIM4 GIM5 PAC10 PFD1 YKE2
    View Details (MIPS) Mewes HW, et al. (2004) GIM3 GIM4 GIM5 PAC10 YKE2
    View Details Krogan NJ, et al. (2006) GIM3 GIM4 GIM5 PAC10 PFD1 YKE2
    View Details Gavin AC, et al. (2006) GIM3 PAC10 YKE2
    View Details Gavin AC, et al. (2002) CDC48 GIM3 GIM5 PAC10 PFK1 SPC110 SPC97 SPC98 TUB4 YKE2
    View Details Qiu et al. (2008) GIM3 GIM4 GIM5 PAC10 PFD1 YKE2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GIM3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle