Protein Overview: NRK1

General Information:
Name(s) found:	NRK1 / YNL129W [SGD]
Description(s) found: Found 30 descriptions. SHOW ALL	Nicotinamide riboside kinase, catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis [SGD]
Organism:	Saccharomyces cerevisiae
Length:	240 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	nicotinamide riboside metabolic process [IDA][IGI]
Molecular Function:	nicotinamide riboside kinase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSKKVILVA LSGCSSSGKT TIAKLTASLF TKATLIHEDD FYKHDNEVPV DAKYNIQNWD  60
   61 SPEALDFKLF GKELDVIKQT GKIATKLIHN NNVDDPFTKF HIDRQVWDEL KAKYDSINDD 120
  121 KYEVVIVDGF MIFNNTGISK KFDLKILVRA PYEVLKKRRA SRKGYQTLDS FWVDPPYYFD 180
  181 EFVYESYRAN HAQLFVNGDV EGLLDPRKSK NIKEFINDDD TPIAKPLSWV CQEILKLCKD 240
  241

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	GBP2	NRK1	1	Unpublished Fields Lab Data
View Screen	HBT1	NRK1	1	Unpublished Fields Lab Data
View Screen	SXM1	NRK1	1	Unpublished Fields Lab Data
View Screen	ATG7	NRK1	1	Unpublished Fields Lab Data
View Screen	PRM3	NRK1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	NRK1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..240]	PSI-BLAST	34.522879	Maltose transport protein MalK, C-terminal domain; Maltose transport protein MalK, N-terminal domain

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
binding	1.89648142312455	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.351319981572451	bayes_pls_golite062009
transcription regulator activity	0.287777990975748	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	0.12351419478929	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2