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Protein Overview: SCJ1

General Information:
Name(s) found: SCJ1 / YMR214W [SGD]
Description(s) found:
Found 14 descriptions.
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  • One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum lumen [IDALink to PubMed article]
    Biological Process: endoplasmic reticulum unfolded protein response [IMPLink to PubMed article]
    protein folding [IMPLink to PubMed article]
    ER-associated protein catabolic process [IMPLink to PubMed article]
    Molecular Function: chaperone binding [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIRCSTDKT WWIGQKSVHW LAKRSRTMIP KLYIHLILSL LLLPLILAQD YYAILEIDKD  60
   61 ATEKEIKSAY RQLSKKYHPD KNAGSEEAHQ KFIEVGEAYD VLSDPEKKKI YDQFGADAVK 120
  121 NGGGGGGPGG PGAGGFHDPF DIFERMFQGG HGGPGGGFGQ RQRQRGPMIK VQEKLSLKQF 180
  181 YSGSSIEFTL NLNDECDACH GSGSADGKLA QCPDCQGRGV IIQVLRMGIM TQQIQQMCGR 240
  241 CGGTGQIIKN ECKTCHGKKV TKKNKFFHVD VPPGAPRNYM DTRVGEAEKG PDFDAGDLVI 300
  301 EFKEKDTENM GYRRRGDNLY RTEVLSAAEA LYGGWQRTIE FLDENKPVKL SRPAHVVVSN 360
  361 GEVEVVKGFG MPKGSKGYGD LYIDYVVVMP KTFKSGQNML KDEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run LST8 No Comments Reinke A, et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] PSI-BLAST 208.450636 DnaJ chaperone, N-terminal (J) domain
    2 View Details [169..246] PSI-BLAST 107.512579 Cysteine-rich domain of the chaperone protein DnaJ.
    3 View Details [247..308] PSI-BLAST 23.39794 Heat shock protein 40 Sis1
    4 View Details [309..404] PSI-BLAST 23.39794 Heat shock protein 40 Sis1


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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