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Protein Overview: IMP1

General Information:
Name(s) found: IMP1 / YMR150C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 190 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane peptidase complex [IDALink to PubMed article]
    Biological Process: protein processing involved in protein targeting to mitochondrion [IDALink to PubMed article]
    Molecular Function: peptidase activity [IDALink to PubMed article]
    mitochondrial inner membrane peptidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVGTLPIWS KTFSYAIRSL CFLHIIHMYA YEFTETRGES MLPTLSATND YVHVLKNFQN  60
   61 GRGIKMGDCI VALKPTDPNH RICKRVTGMP GDLVLVDPST IVNYVGDVLV DEERFGTYIK 120
  121 VPEGHVWVTG DNLSHSLDSR TYNALPMGLI MGKIVAANNF DKPFWDGSIR NIWGFKWINN 180
  181 TFLDVQAKSN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) IMP1 IMP2
    View Details Qiu et al. (2008) IMP1 IMP2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] PSI-BLAST 20.69897 Type 1 signal peptidase
    2 View Details [105..190] ORFEUS 12.95 Type 1 signal peptidase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle