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Protein Overview: MGR3

General Information:
Name(s) found: MGR3 / YMR115W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLQGMRLSQ RLHKRHLFAS KILTWTTNPA HIRHLHDIRP PASNFNTQES APIPESPANS  60
   61 PTRPQMAPKP NLKKKNRSLM YSIIGVSIVG LYFWFKSNSR KQKLPLSAQK VWKEAIWQES 120
  121 DKMDFNYKEA LRRYIEALDE CDRSHVDLLS DDYTRIELKI AEMYEKLNML EEAQNLYQEL 180
  181 LSRFFEALNV PGKVDESERG EVLRKDLRIL IKSLEINKDI ESGKRKLLQH LLLAQEEILS 240
  241 KSPELKEFFE NRKKKLSMVK DINRDPNDDF KTFVSEENIK FDEQGYMILD LEKNSSAWEP 300
  301 FKEEFFTARD LYTAYCLSSK DIAAALSCKI TSVEWMVMAD MPPGQILLSQ ANLGSLFYLQ 360
  361 AEKLEADLNQ LEQKKSKESN QELDMGTYIK AVRFVRKNRD LCLERAQKCY DSVIAFAKRN 420
  421 RKIRFHVKDQ LDPSIAQSIA LSTYGMGVLS LHEGVLAKAE KLFKDSITMA KETEFNELLA 480
  481 EAEKELEKTT VLKAAKKEGL N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MGR3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] deduced N/A No confident structure predictions are available.
    2 View Details [104..210] ORFEUS 9.06 Transcription factor MalT domain III
    3 View Details [211..351] ORFEUS 9.06 Transcription factor MalT domain III
    4 View Details [352..501] ORFEUS 9.06 Transcription factor MalT domain III

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.6263282952649 bayes_pls_golite062009
  • protein binding
    		•  0.816793912043238 bayes_pls_golite062009
  • hydrolase activity
    		•  0.63851966218836 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.397405385912849 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.368200928255565 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle