Protein Overview: NAT4

General Information:
Name(s) found:	NAT4 / YMR069W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|763016\|emb\|CAA88794.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] gi\|6323714\|ref\|NP_013785.1\| N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A; Nat4p [Saccharomyces cerevisiae] [NCBI NR] gi\|45269858\|gb\|AAS56310.1\| YMR069W [Saccharomyces cerevisiae] [NCBI NR] gi\|2497136\|sp\|Q04751.1\|NAT4_YEAST RecName: Full=Histone-specific N-acetyltransferase NAT4 [NCBI NR] gi\|1077998\|pir\|\|S52829 hypothetical protein YMR069w - yeast (Saccharomyces cerevisiae) [NCBI NR] (Q04751) Hypothetical 32.3 kDa protein in NCA1-HMS1 intergenic region [Swiss-Prot] Histone-specific N-acetyltransferase NAT4 OS=Saccharomyces cerevisiae GN=NAT4 PE=1 SV=1 [Swiss-Prot] NAT4 N-alpha acetyltransferase (N-terminal residues of histones H4 and H2A) [mips] N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A [SGD] YMR069W, Chr XIII from 407708-408565 [yeast_orfs2] Chr XIII from 407708-408565 [yeastorf3.fasta] NAT4 SGDID:S0004673, Chr XIII from 407708-408565, Verified ORF [yeastflysequest.fasta] Nat4p [Saccharomyces cerevisiae]gi\|763016\|emb\|CAA88794.1\| unknown [Saccharomyces cerevisiae]gi\|45269858\|gb\|AAS56310.1\| YMR069W [Saccharomyces cerevisiae]gi\|1077998\|pir\|\|S52829 hypothetical protein YMR069w - yeast (Saccharomyces cerevisiae)gi\|2497136\|s [nrdb_11152004_Chlamydomonas] NAT4 SGDID:S000004673, Chr XIII from 407708-408565, Verified ORF, "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Histone-specific N-acetyltransferase NAT4 [nr-271106-contam.fasta] YMR069W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A; Nat4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Histone-specific N-acetyltransferase NAT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAT4 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] NAT4 SGDID:S000004673, Chr XIII from 407709-408566, Genome Release 64-1-1, Verified ORF, "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" [yeast-030211-contam.fasta] NAT4 SGDID:S000004673, Chr XIII from 407709-408566, Genome Release 64-2-1, Verified ORF, "N alpha-acetyl-transferase; involved in acetylation of the N-terminal residues of histones H4 and H2A" [20141208_orf_trans.fasta] YMR069W SGDID:S000004673, Chr XIII from 407709-408566, Genome Release 64-1-1, Verified ORF, "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] N-alpha-acetyltransferase 40 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAT4 PE=1 SV=1 [Swanson-Carlisle-Scereplusabalone-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	285 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	histone acetylation [IDA][IMP]
Molecular Function:	histone acetyltransferase activity [IDA][IMP] transferase activity [IEA] acyltransferase activity [IEA] N-acetyltransferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSVYSENT YNCIRTSKEH LTERRRVAMA PMFQHFLNLC VEKFPESIEH KDTDGNGNFT  60
   61 TAILEREIIY IPEDDTDSID SVDSLKCINY KLHKSRGDQV LDACVQLIDK HLGAKYRRAS 120
  121 RIMYGNRKPW KANKLAEMKS AGLVYVCYWD NGVLGAFTSF MLTEETGLVE GDALHEVSVP 180
  181 VIYLYEVHVA SAHRGHGIGR RLLEHALCDG VARHTRRMCD NFFGVALTVF SDNTRARRLY 240
  241 EALGFYRAPG SPAPASPTIR HTRHGGGRVV VPCDPLYYVY CLHMP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	GPA1	NAT4	2	Unpublished Fields Lab Data
View Screen	LSM8	NAT4	1	Unpublished Fields Lab Data
View Screen	HRT1	NAT4	1	Unpublished Fields Lab Data
View Screen	RAD6	NAT4	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	NAT4	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..128]	deduced	N/A	Confident ab initio structure predictions are available.
2	View Details	[129..285]	PSI-BLAST	10.154902	Aminoglycoside 3-N-acetyltransferase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2