YRC Public Data Repository - Protein Structure Prediction

Protein:	NAT4
Organism:	Saccharomyces cerevisiae
Length:	285 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAT4.

Description	E-value	Query Range	Subject Range
NAT4_YEAST - Histone-specific N-acetyltransferase NAT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G... NAT4 - N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2...	9.0E-98	[1..285]	[1..285]
YJQ4_SCHPO - Uncharacterized N-acetyltransferase C825.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ... SPCC825.04c - N-acetyltransferase	1.0E-32	[61..280]	[13..196]
gi\|12855273 - gi\|12855273\|dbj\|BAB30275.1\| unnamed protein product [Mus musculus]	3.0E-28	[79..253]	[86..238]
MSHD_CORGL - Mycothiol acetyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 ... MSHD_CORGL - Mycothiol acetyltransferase OS=Corynebacterium glutamicum GN=mshD PE=3 SV=1	5.0E-27	[60..249]	[122..285]
gi\|13376119, gi\|... - gi\|13376119\|ref\|NP_079047.1\| N-acetyltransferase 11 [Homo sapiens], gi\|10435991\|dbj\|BAB14720.1\| unna...	2.0E-26	[79..253]	[48..200]
gi\|220959068, gi... - gi\|220959068\|gb\|ACL92077.1\| CG7593-PA [synthetic construct], gi\|220950052\|gb\|ACL87569.1\| CG7593-PA [... CG7593-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7593 (CG7593, FBgn0039687). It is a protein...	5.0E-23	[76..252]	[28..185]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-22	[131..264]	[560..697]
gi\|699204 - gi\|699204\|gb\|AAA62968.1\| u2266n [Mycobacterium leprae]	2.0E-21	[61..246]	[131..297]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSVYSENT YNCIRTSKEH LTERRRVAMA PMFQHFLNLC VEKFPESIEH KDTDGNGNFT  60
   61 TAILEREIIY IPEDDTDSID SVDSLKCINY KLHKSRGDQV LDACVQLIDK HLGAKYRRAS 120
  121 RIMYGNRK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.835	0.411	protein amino acid acetylation	a.1.1	Globin-like

Predicted Domain #2

Region A:
Residues: [129-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PWKANKLAEM KSAGLVYVCY WDNGVLGAFT SFMLTEETGL VEGDALHEVS VPVIYLYEVH  60
   61 VASAHRGHGI GRRLLEHALC DGVARHTRRM CDNFFGVALT VFSDNTRARR LYEALGFYRA 120
  121 PGSPAPASPT IRHTRHGGGR VVVPCDPLYY VYCLHMP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.154902
Match:	1bo4A_
Description:	Aminoglycoside 3-N-acetyltransferase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits