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Protein Overview: COQ5

General Information:
Name(s) found: COQ5 / YML110C [SGD]
Description(s) found:
Found 26 descriptions.
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  • 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    ubiquinone biosynthetic process [IMPLink to PubMed article]
    Molecular Function: 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLISSRIVRS SLVNVPLRLS RCFTQAHRAC KEEEVNSPLS SAAEQPEQKY THFGSKTVLK  60
   61 STKQKLVGDV FSSVANRYDL MNDVMSLGIH RLWKDHFINK LDAGKRPNST TPLNFIDVAG 120
  121 GSGDIAFGLL DHAESKFGDT ESTMDIVDIN PDMLKEGEKR AMEQGKYFKD PRVRFLVSNG 180
  181 EKLEEIDSDS KDIYTVSFGI RNFTDIQKGL NTAYRVLKPG GIFYCLEFSK IENPLMDFAY 240
  241 QQWAKVLPVM GSMIANDYDS YQYLVESIER FPDQETFKSM IEKAGFKSAG YESLTFGICA 300
  301 IHWGIKV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COQ3 COQ5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SNF4 COQ5 2 Uetz P, et al. (2000)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data COQ5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] PSI-BLAST 29.30103 CmaA1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • transferase activity
    		•  1.07321114919891 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.964067575431689 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.612108481676679 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.606225212585352 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.14147363365106 bayes_pls_golite062009
  • binding
    		•  0.109975487409217 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle