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View Structure Prediction Details

Protein: COQ5
Organism: Saccharomyces cerevisiae
Length: 307 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ5.

Description E-value Query
Range
Subject
Range
COQ5_YEAST - 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Saccharomyces cerevisiae (strain ...
COQ5 - 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosy...
4.0E-78 [1..306] [1..306]
gi|220959076 - gi|220959076|gb|ACL92081.1| CG2453-PA [synthetic construct]
FBpp0311953, CG2... - This gene is referred to in FlyBase by the symbol Dmel\CG2453 (CG2453, FBgn0030460). It is a protein...
4.0E-68 [8..307] [1..301]
COQ5_MOUSE - 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Mus musculus GN=Coq5 PE=1 SV=2
3.0E-64 [18..307] [25..327]
UBIE_PASMU - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Pasteurella multocida GN=ubiE PE=3 SV=...
UBIE_PASMU - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Pasteurella multocida (strain Pm70) ...
1.0E-63 [29..306] [8..267]
gi|148231|gb|AAA... - o251 [Escherichia coli]
gi|148231 - gi|148231|gb|AAA67628.1| o251 [Escherichia coli]
2.0E-63 [45..306] [3..250]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ...
UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ...
gi|229508366, gi... - gi|229508366|ref|ZP_04397870.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib...
gi|229346129, gi... - gi|229517066|ref|ZP_04406512.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib...
gi|229520118, gi... - gi|229520118|ref|ZP_04409546.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib...
gi|229527169, gi... - gi|229527169|ref|ZP_04416563.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib...
gi|229369296, gi... - gi|229606641|ref|YP_002877289.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi...
gi|121587669, gi... - gi|121587669|ref|ZP_01677432.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
gi|124115249, gi... - gi|153214643|ref|ZP_01949519.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
gi|254851469, gi... - gi|75829374|ref|ZP_00758679.1| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...
gi|153222877, gi... - gi|153222877|ref|ZP_01953501.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
gi|153801700, gi... - gi|153801700|ref|ZP_01956286.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
gi|116216422, gi... - gi|75823221|ref|ZP_00752740.1| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...
gi|153818222, gi... - gi|153818222|ref|ZP_01970889.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ...
gi|126520347, gi... - gi|229508952|ref|ZP_04398442.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib...
gi|121727801, gi... - gi|75816414|ref|ZP_00746885.1| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...
gi|254291829, gi... - gi|254291829|ref|ZP_04962613.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
gi|153829106, gi... - gi|153829106|ref|ZP_01981773.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1
gi|149739586, gi... - gi|153826648|ref|ZP_01979315.1| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...
3.0E-63 [44..306] [11..259]
UBIE_SALTI - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella typhi GN=ubiE PE=3 SV=1
UBIE_SALTI - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella typhi GN=ubiE PE=3 SV=1
UBIE_SALCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella choleraesuis GN=ubiE PE=3 S...
gi|16762164 - gi|16762164|ref|NP_457781.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella enter...
UBIE_SALTY - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella typhimurium (strain LT2 /...
gi|29139288, gi|... - gi|29143653|ref|NP_806995.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella enter...
gi|238912974 - gi|238912974|ref|ZP_04656811.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
UBIE_SALCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella choleraesuis (strain SC-B...
UBIE_SALPA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella paratyphi A (strain ATCC ...
lcl|NC_016856.1_... - [gene=ubiE] [protein=ubiquinone/menaquinone biosynthesis methyltransferase] [protein_id=YP_005240235...
gi|168822658, gi... - gi|205340946|gb|EDZ27710.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
UBIE_SALNS - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella newport (strain SL254) GN...
UBIE_SALHS - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella heidelberg (strain SL476)...
gi|194470348, gi... - gi|194470348|ref|ZP_03076332.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonel...
gi|197288775, gi... - gi|197288775|gb|EDY28150.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
gi|205336500, gi... - gi|205336500|gb|EDZ23264.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
gi|168263138, gi... - gi|205348076|gb|EDZ34707.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
gi|168467613, gi... - gi|195629964|gb|EDX48624.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
UBIE_SALTY - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella typhimurium GN=ubiE PE=3 SV...
gi|205322164, gi... - gi|205322164|gb|EDZ10003.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
UBIE_SALPB - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella paratyphi B (strain ATCC BA...
gi|205328148, gi... - gi|205328148|gb|EDZ14912.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
UBIE_SALPA - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella paratyphi A GN=ubiE PE=3 SV...
gi|205332091, gi... - gi|205332091|gb|EDZ18855.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonella e...
UBIE_SALCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella choleraesuis GN=ubiE PE=3 S...
UBIE_SALTY - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Salmonella typhimurium GN=ubiE PE=3 SV...
gi|213613265 - gi|213613265|ref|ZP_03371091.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
gi|213646460 - gi|213646460|ref|ZP_03376513.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
UBIE_SALPB - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella paratyphi B (strain ATCC ...
gi|213980489 - gi|213980489|ref|ZP_03407748.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
UBIE_SALPC - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella paratyphi C (strain RKS45...
UBIE_SALEP - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella enteritidis PT4 (strain P...
gi|213023279 - gi|213023279|ref|ZP_03337726.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
gi|213052868 - gi|213052868|ref|ZP_03345746.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
gi|213427342 - gi|213427342|ref|ZP_03360092.1| ubiquinone/menaquinone biosynthesis methyltransferase [Salmonella en...
UBIE_SALDC - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella dublin (strain CT_0202185...
gi|200389228, gi... - gi|200389228|ref|ZP_03215840.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonel...
gi|204320666, gi... - gi|204930262|ref|ZP_03221239.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonel...
UBIE_SALG2 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella gallinarum (strain 287/91...
UBIE_SALSV - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella schwarzengrund (strain CV...
UBIE_SALA4 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella agona (strain SL483) GN=u...
gi|197242042, gi... - gi|197263787|ref|ZP_03163861.1| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Salmonel...
UBIE_SALPK - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Salmonella paratyphi A (strain AKU_1...
3.0E-63 [45..306] [3..250]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-63 [45..306] [3..250]
gi|254699182 - gi|254699182|ref|ZP_05161010.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella abor...
gi|254705477 - gi|254705477|ref|ZP_05167305.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella pinn...
gi|254690622 - gi|254690622|ref|ZP_05153876.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella abor...
gi|254696073 - gi|254696073|ref|ZP_05157901.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella abor...
gi|254732627 - gi|254732627|ref|ZP_05191205.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella abor...
gi|254710710 - gi|254710710|ref|ZP_05172521.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella pinn...
gi|254715888 - gi|254715888|ref|ZP_05177699.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella ceti...
UBIE_BRUA1 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Brucella abortus (strain S19) GN=ubi...
UBIE_BRUA2 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Brucella abortus (strain 2308) GN=ub...
UBIE_BRUAB - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Brucella abortus biovar 1 (strain 9-...
UBIE_BRUME - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Brucella melitensis GN=ubiE PE=3 SV=1
UBIE_BRUAB - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Brucella abortus GN=ubiE PE=3 SV=1
UBIE_BRUMB - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Brucella melitensis biotype 2 (strai...
gi|237817434, gi... - gi|237817434|ref|ZP_04596426.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella abor...
UBIE_BRUME - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Brucella melitensis biotype 1 (strai...
gi|225616009, gi... - gi|225629513|ref|ZP_03787546.1| ubiquinone/menaquinone biosynthesis methyltransferase [Brucella ceti...
1.0E-62 [48..307] [22..269]

Back

Predicted Domain #1
Region A:
Residues: [1-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLISSRIVRS SLVNVPLRLS RCFTQAHRAC KEEEVNSPLS SAAEQPEQKY THFGSKTVLK  60
   61 STKQKLVGDV FSSVANRYDL MNDVMSLGIH RLWKDHFINK LDAGKRPNST TPLNFIDVAG 120
  121 GSGDIAFGLL DHAESKFGDT ESTMDIVDIN PDMLKEGEKR AMEQGKYFKD PRVRFLVSNG 180
  181 EKLEEIDSDS KDIYTVSFGI RNFTDIQKGL NTAYRVLKPG GIFYCLEFSK IENPLMDFAY 240
  241 QQWAKVLPVM GSMIANDYDS YQYLVESIER FPDQETFKSM IEKAGFKSAG YESLTFGICA 300
  301 IHWGIKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.30103
Match: 1kpiA_
Description: CmaA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.25333584501255 bayes_pls_golite062009
transferase activity 1.07321114919891 bayes_pls_golite062009
oxidoreductase activity 0.964067575431689 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.612108481676679 bayes_pls_golite062009
methyltransferase activity 0.606225212585352 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 0.14147363365106 bayes_pls_golite062009
binding 0.109975487409217 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle