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Protein Overview: CDD1

General Information:
Name(s) found: CDD1 / YLR245C [SGD]
Description(s) found:
Found 38 descriptions.
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  • Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 142 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: deoxycytidine catabolic process [IDALink to PubMed article]
    cytidine catabolic process [IDALink to PubMed article]
    pyrimidine salvage [IDALink to PubMed article]
    Molecular Function: cytidine deaminase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVGGIEDRQ LEALKRAALK ACELSYSPYS HFRVGCSILT NNDVIFTGAN VENASYSNCI  60
   61 CAERSAMIQV LMAGHRSGWK CMVICGDSED QCVSPCGVCR QFINEFVVKD FPIVMLNSTG 120
  121 SRSKVMTMGE LLPMAFGPSH LN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CDD1 FCY1
    View Details Noble WS, et al. (2009) Manuscript in preparation. CDD1 SUS1 URM1 gi|14277743, gi|... gi|157829936, gi... gi|160877908, gi... gi|1942461, gi|1... gi|42543757 gi|51247462, gi|... gi|7245349, gi|7...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CDD1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 253.9691 mono-domain cytidine deaminase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytidine deaminase activity
    		•  4.42667374679603 bayes_pls_golite062009
  • deaminase activity
    		•  2.76997916054448 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  2.27736397496642 bayes_pls_golite062009
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • binding
    		•  1.64474382695496 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.51294035758003 bayes_pls_golite062009
  • IMP cyclohydrolase activity
    		•  1.34771936728813 bayes_pls_golite062009
  • hydrolase activity
    		•  1.20889076546073 bayes_pls_golite062009
  • phosphoribosylaminoimidazolecarboxamide formyltransferase activity
    		•  1.06178740854563 bayes_pls_golite062009
  • nucleoside binding
    		•  0.66793245260795 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  0.36832789692523 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  0.308525511259279 bayes_pls_golite062009
  • protein binding
    		•  0.072557222523031 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.0520808212384716 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle