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Protein Overview: UPS2

General Information:
Name(s) found: UPS2 / YLR168C [SGD]
Description(s) found:
Found 35 descriptions.
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  • Mitochondrial intermembrane space protein involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 230 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLFQNSYDF NYPWDQVTAA NWKKYPNEIS THVIAVDVLR RELKDQGKVL VTERLITVKQ  60
   61 GVPKWIMMML GGTNMSHVRE VSVVDLNKKS LTMRSCNLTM CNLLKVYETV TYSPHPDDSA 120
  121 NKTLFQQEAQ ITAYGSIRKL CNKMEDWSVQ RFCENAKKGK MGFDAVLQVF SENWEKHVDD 180
  181 LSNQLVSKVN ETMEDVKISA GTLLKGTERS GRTILQQNID LFRDAYNHEN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ATP14 UPS2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data UPS2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..230] MSA 14.029969 View MSA. No confident structure predictions are available.
    2 View Details [148..230] FFAS03 1.05 Human micelle-bound alpha-synuclein


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle