YRC Public Data Repository - Protein Structure Prediction

Protein:	UPS2
Organism:	Saccharomyces cerevisiae
Length:	230 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPS2.

Description	E-value	Query Range	Subject Range
UPS2 - Mitochondrial intermembrane space protein involved in regulation of mitochondrial cardiolipin and ph... gi\|190405240 - gi\|190405240\|gb\|EDV08507.1\| protein MSF1 [Saccharomyces cerevisiae RM11-1a] gi\|207343005 - gi\|207343005\|gb\|EDZ70602.1\| YLR168Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|151941014 - gi\|151941014\|gb\|EDN59394.1\| conserved protein [Saccharomyces cerevisiae YJM789] UPS2_YEAST - Protein UPS2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UPS2 PE=1 SV...	1.0E-87	[1..230]	[1..230]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-67	[2..197]	[3..201]
PRLD1_MOUSE - PRELI domain-containing protein 1, mitochondrial OS=Mus musculus GN=Prelid1 PE=1 SV=1	8.0E-66	[1..179]	[2..179]
gi\|209736870 - gi\|209736870\|gb\|ACI69304.1\| PRELI domain-containing protein 1, mitochondrial precursor [Salmo salar] PRELID1 - PRELI domain containing 1 gi\|123995091, gi... - gi\|123995091\|gb\|ABM85147.1\| px19-like protein [synthetic construct], gi\|123980278\|gb\|ABM81968.1\| px1...	2.0E-65	[1..179]	[2..179]
slmo-PC, slmo-PB... - The gene slowmo is referred to in FlyBase by the symbol Dmel\slmo (CG9131, FBgn0029161). It is a pro... gi\|195342908, gi... - gi\|195342908\|ref\|XP_002038040.1\| GM17966 [Drosophila sechellia], gi\|194132890\|gb\|EDW54458.1\| GM17966... gi\|194190326, gi... - gi\|195576912\|ref\|XP_002078317.1\| GD22604 [Drosophila simulans], gi\|194190326\|gb\|EDX03902.1\| GD22604 ... gi\|220945270, gi... - gi\|220955084\|gb\|ACL90085.1\| slmo-PA [synthetic construct], gi\|220945270\|gb\|ACL85178.1\| slmo-PA [synt...	9.0E-59	[1..199]	[1..197]

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Predicted Domain #1

Region A:
Residues: [1-230]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLFQNSYDF NYPWDQVTAA NWKKYPNEIS THVIAVDVLR RELKDQGKVL VTERLITVKQ  60
   61 GVPKWIMMML GGTNMSHVRE VSVVDLNKKS LTMRSCNLTM CNLLKVYETV TYSPHPDDSA 120
  121 NKTLFQQEAQ ITAYGSIRKL CNKMEDWSVQ RFCENAKKGK MGFDAVLQVF SENWEKHVDD 180
  181 LSNQLVSKVN ETMEDVKISA GTLLKGTERS GRTILQQNID LFRDAYNHEN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [148-230]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVQRFCENAK KGKMGFDAVL QVFSENWEKH VDDLSNQLVS KVNETMEDVK ISAGTLLKGT  60
   61 ERSGRTILQQ NIDLFRDAYN HEN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.05
Match:	1xq8A
Description:	Human micelle-bound alpha-synuclein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits