YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PUS5

General Information:
Name(s) found: PUS5 / YLR165C [SGD]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 254 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IMPLink to PubMed article]
    Biological Process: rRNA modification [IMPLink to PubMed article]
    pseudouridine synthesis [IMPLink to PubMed article]
    Molecular Function: pseudouridylate synthase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKKQIPII FENTHYFIVN KPPGIPSQPP DCRTWGRTHP NLDPTPLLER FKAIYYSHRE  60
   61 VELCRTVHRL DHCVTGGMLI AKTKDGSVKF SRFLQKGGNN GYKLQRKYVA IVESSGRFNK 120
  121 PNNYEIKYGP KYNFLISHGG REITKFKEVD ENCIVLQLVT GKKHQIRNHV SQILNQPILN 180
  181 DKRHGSTVNF PELFNDQIAL HSACIITKIG LQTKTHLIPM EHNNTGQLWS RKYVNEEGEF 240
  241 TLPIKEVLLE NWDQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..254] PSI-BLAST 16.221849 Ribosomal small subunit pseudouridine 516 synthase RsuA; Pseudouridine synthase RsuA N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.19957135839682 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  3.78688422405974 bayes_pls_golite062009
  • isomerase activity
    		•  2.91720316078381 bayes_pls_golite062009
  • catalytic activity
    		•  2.02180970970004 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.61345420467196 bayes_pls_golite062009
  • DNA binding
    		•  0.359897611264802 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.326696802363771 bayes_pls_golite062009
  • binding
    		•  0.301411339531862 bayes_pls_golite062009
  • RNA binding
    		•  0.195784910723548 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle