Protein Overview: YPS1

General Information:
Name(s) found:	YPS1 / YLR120C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6323149\|ref\|NP_013221.1\| Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; Yps1p [Saccharomyces cerevisiae] [NCBI NR] gi\|2507240\|sp\|P32329.2\|YPS1_YEAST RecName: Full=Aspartic proteinase 3; AltName: Full=Yapsin-1; AltName: Full=Proprotein convertase; Contains: RecName: Full=Aspartic proteinase 3 subunit alpha; Contains: RecName: Full=Aspartic proteinase 3 subunit beta; Fl [NCBI NR] pir\|\|S64957 aspergillopepsin I (EC 3.4.23.18) YAP3 precursor - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1360522\|emb\|CAA97688.1\| YAP3 [Saccharomyces cerevisiae] [NCBI NR] gi\|1297035\|emb\|CAA61699.1\| Aspartyl protease [Saccharomyces cerevisiae] [NCBI NR] gi\|1256861\|gb\|AAB82367.1\| Yap3p: aspartic proteinase [Saccharomyces cerevisiae] [NCBI NR] Aspartic proteinase 3 OS=Saccharomyces cerevisiae GN=YPS1 PE=1 SV=2 [Swiss-Prot] YPS1 Aspergillopepsin [mips] Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor [SGD] YPS1, Chr XII from 386512-388221, reverse complement [yeast_orfs2] Chr XII from 386512-388221, reverse complement [yeastorf3.fasta] Chr XII from 388221-386512, reverse complement [yeastorf5.fasta] (P32329) Aspartic proteinase 3 precursor (EC 3.4.23.41) (Yapsin 1) [4932.FASTACCERV.txt] YPS1 SGDID:S0004110, Chr XII from 388221-386512, reverse complement, Verified ORF [yeastflysequest.fasta] Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor [Saccharomyces cerevisiae]gi\|1297035\|emb\|CAA61699.1\| Aspartyl protease [Saccharomyces cerevisiae]gi\|1360522\|emb\|CAA97688.1\| YAP3 [Saccharomyces cerevisiae [nrdb_11152004_Chlamydomonas] YPS1 SGDID:S000004110, Chr XII from 388221-386512, reverse complement, Verified ORF, "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; Yps1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YAP3 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yap3p: aspartic proteinase [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Aspartic proteinase 3 precursor (Yapsin-1) [nr-271106-contam.fasta] Aspartyl protease [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Aspartic proteinase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YPS1 SGDID:S000004110, Chr XII from 388220-386511, Genome Release 64-1-1, reverse complement, Verified ORF, "Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" [yeast-030211-contam.fasta] YPS1 SGDID:S000004110, Chr XII from 388220-386511, Genome Release 64-2-1, reverse complement, Verified ORF, "Aspartic protease; member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; YPS1 has a paralog, MKC7, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR6318\|c0_g1_i1\|g.4470 ORF TR6318\|c0_g1_i1\|g.4470 TR6318\|c0_g1_i1\|m.4470 type:complete len:570 (+) TR6318\|c0_g1_i1:283-1992(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YLR120C SGDID:S000004110, Chr XII from 388220-386511, Genome Release 64-1-1, reverse complement, Verified ORF, "Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_8645\|g.6133 ORF asmbl_8645\|g.6133 asmbl_8645\|m.6133 type:complete len:570 (+) asmbl_8645:289-1998(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_8645\|g.5264 ORF ID=asmbl_8645\|g.5264 ID=asmbl_8645\|m.5264 type:complete len:570 (+) ID=asmbl_8645:289-1998(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	569 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA]
Biological Process:	protein processing [IDA]
Molecular Function:	aspartic-type endopeptidase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLKTVRSAV LSSLFASQVL GKIIPAANKR DDDSNSKFVK LPFHKLYGDS LENVGSDKKP  60
   61 EVRLLKRADG YEEIIITNQQ SFYSVDLEVG TPPQNVTVLV DTGSSDLWIM GSDNPYCSSN 120
  121 SMGSSRRRVI DKRDDSSSGG SLINDINPFG WLTGTGSAIG PTATGLGGGS GTATQSVPAS 180
  181 EATMDCQQYG TFSTSGSSTF RSNNTYFSIS YGDGTFASGT FGTDVLDLSD LNVTGLSFAV 240
  241 ANETNSTMGV LGIGLPELEV TYSGSTASHS GKAYKYDNFP IVLKNSGAIK SNTYSLYLND 300
  301 SDAMHGTILF GAVDHSKYTG TLYTIPIVNT LSASGFSSPI QFDVTINGIG ISDSGSSNKT 360
  361 LTTTKIPALL DSGTTLTYLP QTVVSMIATE LGAQYSSRIG YYVLDCPSDD SMEIVFDFGG 420
  421 FHINAPLSSF ILSTGTTCLL GIIPTSDDTG TILGDSFLTN AYVVYDLENL EISMAQARYN 480
  481 TTSENIEIIT SSVPSAVKAP GYTNTWSTSA SIVTGGNIFT VNSSQTASFS GNLTTSTASA 540
  541 TSTSSKRNVG DHIVPSLPLT LISLLFAFI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		YET3 YPS1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	YPS1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..139]	ORFEUS	14.75	(Pro)phytepsin; Plant acid proteinase, phytepsin
2	View Details	[140..152] [290..326] [460..492]	PSI-BLAST	1346.522879	No description for 1ypsA_ was found.
3	View Details	[153..289] [327..459]	PSI-BLAST	1346.522879	No description for 1ypsA_ was found.
4	View Details	[493..569]	deduced	N/A	No confident structure predictions are available.

Protein Overview: YPS1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: