Protein Overview: YLR118C

General Information:
Name(s) found:	YLR118C [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS [SGD]
Organism:	Saccharomyces cerevisiae
Length:	227 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	palmitoyl-(protein) hydrolase activity [IDA][IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGLRVAAKI QPARQTIIFL HGLGDTGSGW GFLAQYLQQR DPAAFQHTNF VFPNAPELHV  60
   61 TANGGALMPA WFDILEWDPS FSKVDSDGFM NSLNSIEKTV KQEIDKGIKP EQIIIGGFSQ 120
  121 GAALALATSV TLPWKIGGIV ALSGFCSIPG ILKQHKNGIN VKTPIFHGHG DMDPVVPIGL 180
  181 GIKAKQFYQD SCEIQNYEFK VYKGMAHSTV PDELEDLASF IKKSLSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PRP16	YLR118C	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YLR118C	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..227]	PSI-BLAST	362.502279	Acyl protein thioesterase 1

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
hydrolase activity	2.24106351016868	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity	0.277033874372149	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2