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Protein Overview: AVL9

General Information:
Name(s) found: AVL9 / YLR114C [SGD]
Description(s) found:
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  • gi|74676611|sp|Q12500.1|AVL9_YEAST RecName: Full=Late secretory pathway protein AVL9; AltName: Full=APL2 VPS1 synthetic lethal protein 9 [NCBI NR]
  • gi|6323143|ref|NP_013215.1| Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; Avl9p [Saccharomyces cerevis [NCBI NR]
  • pir||S64951 hypothetical protein YLR114c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1360510|emb|CAA97681.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1297028|emb|CAA61692.1| L2941 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1256877|gb|AAB67559.1| Ylr114cp [Saccharomyces cerevisiae] [NCBI NR]
  • Late secretory pathway protein AVL9 OS=Saccharomyces cerevisiae GN=AVL9 PE=1 SV=1 [Swiss-Prot]
  • AVL9 Protein of unknown function localised to cytoplasm [mips]
  • Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms [SGD]
  • EFR4, Chr XII from 374945-377239, reverse complement [yeast_orfs2]
  • Chr XII from 374945-377239, reverse complement [yeastorf3.fasta]
  • Chr XII from 377239-374945, reverse complement [yeastorf5.fasta]
  • >Q12500 (Q12500) Chromosome XII reading frame ORF YLR114C [4932.FASTACCERV.txt]
  • YLR114C SGDID:S0004104, Chr XII from 377239-374945, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • PHO85 Requiring [Saccharomyces cerevisiae]gi|1297028|emb|CAA61692.1| L2941 [Saccharomyces cerevisiae]gi|1360510|emb|CAA97681.1| unnamed protein product [Saccharomyces cerevisiae]gi|2131781|pir||S64951 hypothetical protein YLR114c - yeast (Saccharomyces [nrdb_11152004_Chlamydomonas]
  • (Q12500) S.cerevisiae chromosome XII reading frame ORF YLR114c (Ylr114cp) (L2941 protein) [cerv4932.FASTAC]
  • YLR114C SGDID:S000004104, Chr XII from 377239-374945, reverse complement, Uncharacterized ORF, "Mutation is syntheticly lethal with apl2 vps1 double mutant" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • AVL9 SGDID:S000004104, Chr XII from 377239-374945, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with or [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Ylr114cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Mutation is syntheticly lethal with apl2 vps1 double mutant; Avl9p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein AVL9 (APL2 VPS1 synthetic lethal protein 9) [nr-271106-contam.fasta]
  • L2941 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • AVL9 SGDID:S000004104, Chr XII from 377239-374945, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Late secretory pathway protein AVL9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVL9 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • AVL9 SGDID:S000004104, Chr XII from 377238-374944, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms" [yeast-030211-contam.fasta]
  • AVL9 SGDID:S000004104, Chr XII from 377238-374944, Genome Release 64-2-1, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress" [20141208_orf_trans.fasta]
  • YLR114C SGDID:S000004104, Chr XII from 377238-374944, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 764 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: post-Golgi vesicle-mediated transport [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEHEEAVIF GICLVDFHHK RGPEIEYWYG LPEGTQSAEL WPNLPFQALP DGSHSFEETF  60
   61 TYFTLLYDER RQRSPPNGAT DLSDDSINDN TTLFAISCSR QIKSDELVTK DKDVTRSTVQ 120
  121 KAIVVISRQP IFGQIKDKLS IVTNAFFLQH DFGDRKIIQS LYENLKSIYT PASLVRNAEN 180
  181 RLYIGLCLRK ILHDFKRNAL VLLKAIMLEK KIIVYGNDVE ALCNLQFGLI SLIPDLMSNL 240
  241 QDSGSPQLFQ DISKLNVVDS FKSSNRESVL RFLGFPLPIF EKGGLFSPYT PLQQMNDIRS 300
  301 ERTLFFMIGS SNTLLAEQKE ELCHIFVNTD NSTVDILDKT LNPVLQLSSH DKKWIESISG 360
  361 IVSDTWNEND DETPKNSQFE GSEDFIRWQF EDYLTGLLSS VKLSDYLDLH KENDQALKTI 420
  421 PEDMLNSNPV HLFNLNWVQS WKETQNFLIF NSRTDDRLFD LFPPKHIYNG ADTLSLLQQR 480
  481 FLATFHNLKR SSSNSSSNKN GHQSEEDIKD QESIESKKSV SQISVNPGKN TDKPAANLWN 540
  541 SWKEYFNKPK NTANEDVTES TEDLKNRSKT SNAIQKAMMG LGLHYKPDAE TDQQSEEVGN 600
  601 SEDNEDDDTD EDSEDDDDDG GDDDDSEDDD DDDDGEGDEN GDDGEGDENG DDGEGDENGD 660
  661 KEDSQDFSNG FTDVTNINTD HDKENEQNFE GNAENFNEDE TVADKDIEGG PESNKNSDSK 720
  721 TDIYENDRNV EDSSKTRNTV KKSNEEGGAN DAAIGNCVQD EEKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AVL9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 5.012964 View MSA. No confident structure predictions are available.
    2 View Details [170..287] deduced N/A No confident structure predictions are available.
    3 View Details [288..764] MSA 34.164997 View MSA. No confident structure predictions are available.
    4 View Details [429..597] MSA 1.183997 View MSA. No confident structure predictions are available.
    5 View Details [598..764] MSA 2.181995 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle