YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: GTT2

General Information:
Name(s) found: GTT2 / YLL060C [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 233 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: glutathione metabolic process [IDALink to PubMed article]
    Molecular Function: glutathione transferase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGRGFLIYN GGEKMKQKMI IYDTPAGPYP ARVRIALAEK NMLSSVQFVR INLWKGEHKK  60
   61 PEFLAKNYSG TVPVLELDDG TLIAECTAIT EYIDALDGTP TLTGKTPLEK GVIHMMNKRA 120
  121 ELELLDPVSV YFHHATPGLG PEVELYQNKE WGLRQRDKAL HGMHYFDTVL RERPYVAGDS 180
  181 FSMADITVIA GLIFAAIVKL QVPEECEALR AWYKRMQQRP SVKKLLEIRS KSS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CDC21 GTT2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GTT2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] PSI-BLAST 128.228787 Class phi GST
    2 View Details [100..233] PSI-BLAST 128.228787 Class phi GST

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • disulfide oxidoreductase activity
    		•  2.75329559672625 bayes_pls_golite062009
  • antioxidant activity
    		•  1.96600066476624 bayes_pls_golite062009
  • glutathione transferase activity
    		•  1.85683051472829 bayes_pls_golite062009
  • peroxidase activity
    		•  1.63725317384157 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  1.63725317384157 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.44229450804826 bayes_pls_golite062009
  • glutathione binding
    		•  1.1614557144978 bayes_pls_golite062009
  • binding
    		•  0.828696005067827 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  0.527635650858282 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  0.366096607480921 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  0.163136748643487 bayes_pls_golite062009
  • hydrolase activity
    		•  0.150237022038507 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  0.13913802190798 bayes_pls_golite062009
  • protein binding
    		•  0.134341907247724 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle