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View Structure Prediction Details

Protein: GTT2
Organism: Saccharomyces cerevisiae
Length: 233 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTT2.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-58 [15..231] [1..204]
gi|38679413, gi|... - gi|38679413|gb|AAR26528.1| glutathione S-transferase [Glycine max], gi|11385435|gb|AAG34800.1|AF2433...
1.0E-56 [15..231] [1..204]
GSTF_HYOMU - Glutathione S-transferase OS=Hyoscyamus muticus PE=1 SV=1
6.0E-56 [19..230] [3..212]
gi|1737447 - gi|1737447|gb|AAB38965.1| auxin-induced protein [Eucalyptus globulus]
7.0E-55 [15..231] [1..205]
gi|14538027, gi|... - gi|5923877|gb|AAD56395.1|AF184059_1 glutathione S-transferase [Triticum aestivum], gi|14538027|gb|AA...
2.0E-54 [17..231] [2..212]
gi|17385642 - gi|17385642|dbj|BAB32446.2| glutathione S-transferase [Matricaria chamomilla]
2.0E-54 [19..231] [6..206]
gi|8052535 - gi|8052535|gb|AAF71799.1|AC013430_8 F3F9.13 [Arabidopsis thaliana]
2.0E-54 [15..231] [1..204]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGRGFLIYN GGEKMKQKMI IYDTPAGPYP ARVRIALAEK NMLSSVQFVR INLWKGEHKK  60
   61 PEFLAKNYSG TVPVLELDDG TLIAECTAIT EYIDALDGT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.228787
Match: 1byeA_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
disulfide oxidoreductase activity 2.75329559672625 bayes_pls_golite062009
antioxidant activity 1.96600066476624 bayes_pls_golite062009
glutathione transferase activity 1.85683051472829 bayes_pls_golite062009
peroxidase activity 1.63725317384157 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 1.63725317384157 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.44229450804826 bayes_pls_golite062009
glutathione binding 1.1614557144978 bayes_pls_golite062009
binding 0.828696005067827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
glutathione peroxidase activity 0.527635650858282 bayes_pls_golite062009
peroxiredoxin activity 0.366096607480921 bayes_pls_golite062009
thioredoxin peroxidase activity 0.163136748643487 bayes_pls_golite062009
hydrolase activity 0.150237022038507 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.13913802190798 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [100-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTLTGKTPLE KGVIHMMNKR AELELLDPVS VYFHHATPGL GPEVELYQNK EWGLRQRDKA  60
   61 LHGMHYFDTV LRERPYVAGD SFSMADITVI AGLIFAAIVK LQVPEECEAL RAWYKRMQQR 120
  121 PSVKKLLEIR SKSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.228787
Match: 1byeA_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle