Protein Overview: COS9

General Information:
Name(s) found:	COS9 / YKL219W [SGD]
Description(s) found: Found 27 descriptions. SHOW ALL	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins [SGD]
Organism:	Saccharomyces cerevisiae
Length:	407 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIVRSCNSN NKPLIPSSNW HIAIRMRGDG VKDRSIDVLS LKHFESQKVV LPQDLFMDNF  60
   61 TWMFYEFFKC FTFRTWLLLL LLMWLPGFLS QIKSINRIFP FKLCILVSCL VGIFLPNIYS 120
  121 FSHKSVLTNQ LTQFSKEIVE HAPGTDTHDW ETVAANLNSY FYENKAWNTE YFFFNAAECQ 180
  181 KAFRKVLLEP FSVKKDESSK IKSFGDSVPY IEEALQVYST EFDKKWKLFN TEKVWSPDNL 240
  241 EHVQLPKKTY RYKFTWVLKR IFNLWLFPAF ILFLACIYVS WDKGHLFRIL CCGGGFLLMV 300
  301 RVFQNMRPFS MHMEDKMQFL STIINEQESG ANGWDEIAKK MNRYLFEKKV WTSEEFFFDG 360
  361 IDCEWFFNHF FYRLLSTKKP MFDRPLNVEL WPYIKEAQLT RKQAPPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BUR2	COS9	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..89]	MSA	1.017988	View MSA. No confident structure predictions are available.
2	View Details	[90..199]	Pfam	49.356547	DUP family Confident ab initio structure predictions are available.
3	View Details	[200..272]	deduced	N/A	No confident structure predictions are available.
4	View Details	[273..407]	Pfam	59.481486	DUP family No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2