Protein Overview: DAN4

General Information:
Name(s) found:	DAN4 / YJR151C [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth [SGD]
Organism:	Saccharomyces cerevisiae
Length:	1161 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNISIVAGI VALATSAAAI TATTTLSPYD ERVNLIELAV YVSDIRAHIF QYYSFRNHHK  60
   61 TETYPSEIAA AVFDYGDFTT RLTGISGDEV TRMITGVPWY STRLKPAISS ALSKDGIYTA 120
  121 IPTSTSTTTT KSSTSTTPTT TITSTTSTTS TTPTTSTTST TPTTSTTSTT PTTSTTSTTP 180
  181 TTSTTSTTPT TSTTSTTPTT STTSTTPTTS TTSTTPTTST TSTTPTTSTT PTTSTTSTTS 240
  241 QTSTKSTTPT TSSTSTTPTT STTPTTSTTS TAPTTSTTST TSTTSTISTA PTTSTTSSTF 300
  301 STSSASASSV ISTTATTSTT FASLTTPATS TASTDHTTSS VSTTNAFTTS ATTTTTSDTY 360
  361 ISSSSPSQVT SSAEPTTVSE VTSSVEPTRS SQVTSSAEPT TVSEFTSSVE PTRSSQVTSS 420
  421 AEPTTVSEFT SSVEPTRSSQ VTSSAEPTTV SEFTSSVEPT RSSQVTSSAE PTTVSEFTSS 480
  481 VEPTRSSQVT SSAEPTTVSE FTSSVEPIRS SQVTSSAEPT TVSEVTSSVE PIRSSQVTTT 540
  541 EPVSSFGSTF SEITSSAEPL SFSKATTSAE SISSNQITIS SELIVSSVIT SSSEIPSSIE 600
  601 VLTSSGISSS VEPTSLVGPS SDESISSTES LSATSTFTSA VVSSSKAADF FTRSTVSAKS 660
  661 DVSGNSSTQS TTFFATPSTP LAVSSTVVTS STDSVSPNIP FSEISSSPES STAITSTSTS 720
  721 FIAERTSSLY LSSSNMSSFT LSTFTVSQSI VSSFSMEPTS SVASFASSSP LLVSSRSNCS 780
  781 DARSSNTISS GLFSTIENVR NATSTFTNLS TDEIVITSCK SSCTNEDSVL TKTQVSTVET 840
  841 TITSCSGGIC TTLMSPVTTI NAKANTLTTT ETSTVETTIT TCPGGVCSTL TVPVTTITSE 900
  901 ATTTATISCE DNEEDITSTE TELLTLETTI TSCSGGICTT LMSPVTTINA KANTLTTTET 960
  961 STVETTITTC SGGVCSTLTV PVTTITSEAT TTATISCEDN EEDVASTKTE LLTMETTITS1020
 1021 CSGGICTTLM SPVSSFNSKA TTSNNAESTI PKAIKVSCSA GACTTLTTVD AGISMFTRTG1080
 1081 LSITQTTVTN CSGGTCTMLT APIATATSKV ISPIPKASSA TSIAHSSASY TVSINTNGAY1140
 1141 NFDKDNIFGT AIVAVVALLL L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RCY1	DAN4	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..125]	Pfam	63.744727	Seripauperin and TIP1 family Confident ab initio structure predictions are available.
2	View Details	[126..235]	deduced	N/A	No confident structure predictions are available.
3	View Details	[236..623]	MSA	6.209996	View MSA. No confident structure predictions are available.
4	View Details	[624..862]	MSA	1.172997	View MSA. No confident structure predictions are available.
5	View Details	[863..1161]	MSA	4.127993	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2