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Protein Overview: XPT1

General Information:
Name(s) found: XPT1 / YJR133W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 209 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: hypoxanthine metabolic process [IGILink to PubMed article]
    XMP salvage [IMPLink to PubMed article]
    Molecular Function: xanthine phosphoribosyltransferase activity [IMPLink to PubMed article]
    hypoxanthine phosphoribosyltransferase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENERMYIS YNNIHKLCQG VAKHILARNE RPDIIIAITG GGMIPARIIR SFLKTKGQKN  60
   61 IPIQAIGLSL YEDLGLDNSV ETIGKEVIRT QWLDFGALNQ HFDSLIGKKV LIVDEVDDTR 120
  121 TTLHYAVSEL EKEIAEQQKV LNRMSEETVI SIFVLHNKDK PKRAGLPDSM MNSGRYIAAQ 180
  181 TVPDKWLCYP WDAEDIEEHT MLAKAQGHD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) HPT1 XPT1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data XPT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..209] PSI-BLAST 32.39794 Hypoxantine-guanine PRTase (HGPRTase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring glycosyl groups
    		•  3.91023158228049 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  3.89356447922614 bayes_pls_golite062009
  • adenine phosphoribosyltransferase activity
    		•  3.83339863213875 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • uracil phosphoribosyltransferase activity
    		•  2.36237864658341 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • transferase activity
    		•  2.03376808731027 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  1.51802880667162 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.18255665419929 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • purine binding
    		•  0.745430157183377 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.552133387792911 bayes_pls_golite062009
  • binding
    		•  0.535390228935555 bayes_pls_golite062009
  • DNA binding
    		•  0.439741935655503 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.396538943915776 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle