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Protein Overview: STR2

General Information:
Name(s) found: STR2 / YJR130C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Cystathionine gamma-synthase, converts cysteine into cystathionine [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: sulfur metabolic process [IMPLink to PubMed article]
    Molecular Function: cystathionine gamma-synthase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISRTIGESI PPNTKHAVSV CLPTWEATVG YEEGESSIIN SLTTGYPRFF IHKSIKKLCE  60
   61 ILSAKYSMED EACLCFPSYK VANRCREFIK VKTGLSTKVR ILQLCTPKPM NQEEKLWRRE 120
  121 CKITVVFVDQ EIFPVMKQYW QHSGEIVSSR MAEYILHELQ VKDNLKKMET VDNGKKFMTE 180
  181 DENRVNEEYI ETRFGRNLNF LAADKAKYLI RKRIATKVVE KIDSEGLSDL FSFEHYNESN 240
  241 GPFNVGSGEA LDDDQLNSDI PAETITSMGE SGSNSTFENT ATDDLKFHVN PNTDVYLFPS 300
  301 GMASIFTAHR LLLNFDAKRL SRSSSRQDKL IGYGPPFKKT VMFGFPYTDT LSILRKFNHT 360
  361 HFLGQGDSTS MNALKNILHS GEQILAVFIE APSNPLLKMG DLQELKRLSD LYSFYIVVDE 420
  421 TVGGFVNIDV LPYADIVCSS LTKIFSGDSN VIAGSLVLNP RGKIYEFARK FMKTEDGYED 480
  481 CLWCEDALCL ERNSRDFVER TIKVNTNTDI LLKRVLLPQV GKLFKKIYYP SLTSEDTKRN 540
  541 YDSVMSTKDG GYGGLFSLTF FNIEEAKKFF NNLELCKGPS LGTNFTLACP YAIIAHYQEL 600
  601 DEVAQYGVET NLVRVSVGLE NSDVLCNVFQ RAIEKALGE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data STR2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 2.221849 Prepeptide of 5-ALAS
    2 View Details [108..180] deduced N/A No confident structure predictions are available.
    3 View Details [181..501] PSI-BLAST 208.457575 Methionine gamma-lyase, MGL
    4 View Details [502..639] PSI-BLAST 208.457575 Methionine gamma-lyase, MGL


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle